Literature DB >> 16498245

Potential clinical correlates and risk factors for interatrial block.

Vignendra Ariyarajah1, Sirin Apiyasawat, Ranjani Moorthi, David H Spodick.   

Abstract

BACKGROUND: Interatrial block (IAB; P wave > or =110 ms) denotes a conduction delay between the atria, is strongly associated with atrial tachyarrhythmias, left atrial enlargement, left atrial electromechanical dysfunction, and is a risk for embolism. Despite this, potential risk factors for IAB have not been clearly defined.
METHODS: Patients admitted via the Emergency Department for nonacute medical reasons to the nontelemetry general medical floors of a tertiary care general hospital from October to November 2004 were screened for sinus rhythm on electrocardiograms. Four hundred and four patients who met our criteria were then evaluated for IAB on respective electrocardiograms. All patients were subsequently compared for common diseases as well as coronary artery disease (CAD) risk factors and divided into two groups, those with IAB and those without (control). Mean age +/- standard deviation, odds ratios (ORs), 95% confidence intervals (CIs), r values, and p values were calculated. p values <0.05 were considered statistically significant.
RESULTS: From the sample (n = 404), 182 patients had IAB (45%; mean age 64.32 +/- 19.27 years; males 51.6%) while 222 did not (control). CAD (OR 3.150, 95% CI 2.05-4.83; p < 0.001, r = 0.3), hypertension (OR 2.918, 95% CI 1.85-4.60; p < 0.001, r = 0.2), diabetes mellitus (OR 2.542, 95% CI 1.62-3.97; p < 0.001, r = 0.1), and hypercholesterolemia (OR 1.823, 95% CI 1.22-2.74; p = 0.004, r = 0.2) were significant risk factors and correlates for IAB. Multivariate analysis using stepwise linear regression revealed these factors as direct correlates of IAB.
CONCLUSION: CAD, hypertension, diabetes mellitus and hypercholesterolemia appear to be risk factors for IAB in general hospital patients admitted for nonacute reasons. Considering the known sequelae of IAB, awareness of its associations with such risk factors could be important for patient risk stratification. Copyright 2006 S. Karger AG, Basel.

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Year:  2006        PMID: 16498245     DOI: 10.1159/000091642

Source DB:  PubMed          Journal:  Cardiology        ISSN: 0008-6312            Impact factor:   1.869


  7 in total

1.  The prevalence and prognostic significance of interatrial block in the general population.

Authors:  Tiia Istolahti; Antti Eranti; Heini Huhtala; Leo-Pekka Lyytikäinen; Mika Kähönen; Terho Lehtimäki; Markku Eskola; Ismo Anttila; Antti Jula; Antoni Bayés de Luna; Kjell Nikus; Jussi Hernesniemi
Journal:  Ann Med       Date:  2020-03-14       Impact factor: 4.709

Review 2.  Intra- and interatrial conduction abnormalities: hemodynamic and arrhythmic significance.

Authors:  Nicolas Johner; Mehdi Namdar; Dipen C Shah
Journal:  J Interv Card Electrophysiol       Date:  2018-08-20       Impact factor: 1.900

3.  Interatrial block - a novel risk factor for acute mesenteric ischemia.

Authors:  Lovely Chhabra; Indu Srinivasan; Pooja Sareen; Curuchi Anand; David H Spodick
Journal:  Indian J Gastroenterol       Date:  2012-07-05

4.  Potential factors that affect electrocardiographic progression of interatrial block.

Authors:  Vignendra Ariyarajah; Mark Kranis; Sirin Apiyasawat; David H Spodick
Journal:  Ann Noninvasive Electrocardiol       Date:  2007-01       Impact factor: 1.468

5.  Interatrial block: a novel risk factor for embolic stroke?

Authors:  Vignendra Ariyarajah; Puneet Puri; Sirin Apiyasawat; David H Spodick
Journal:  Ann Noninvasive Electrocardiol       Date:  2007-01       Impact factor: 1.468

Review 6.  Electrophysiological Mechanisms of Bayés Syndrome: Insights from Clinical and Mouse Studies.

Authors:  Gary Tse; Eric Tsz Him Lai; Jie Ming Yeo; Bryan P Yan
Journal:  Front Physiol       Date:  2016-05-31       Impact factor: 4.566

7.  Independent associations of blood pressure and body mass index with interatrial block: a cross-sectional study in general Chinese population.

Authors:  Guozhe Sun; Ying Zhou; Ning Ye; Shaojun Wu; Yingxian Sun
Journal:  BMJ Open       Date:  2019-07-02       Impact factor: 2.692

  7 in total

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