AIM: To study whether surgical treatment at age 9 mo in boys with congenital unilaterally palpable undescended testes (cryptorchidism) is followed by improved growth of the previously retained testes compared to non-treatment. METHODS: At the age of 6 mo, 70 boys were randomized to surgical treatment at 9 mo and 79 boys to treatment at 3 y of age. The boys were then followed at 12 and 24 mo. Ultrasonography was used to determine testicular volume. RESULTS: After orchidopexy, the previously retained testes resumed growth and were significantly larger than the non-operated testes at 2 y (0.49 ml vs 0.36 ml, p<0.001). Testicular growth after orchidopexy was also demonstrated by a higher mean ratio between the previously retained and the scrotal testes of the individual boys at 2 y: 0.84 for the surgically treated group, compared to 0.63 for the untreated group (p<0.001). CONCLUSION: Surgery at 9 mo has a beneficial effect on the growth of previously undescended testes.
RCT Entities:
AIM: To study whether surgical treatment at age 9 mo in boys with congenital unilaterally palpable undescended testes (cryptorchidism) is followed by improved growth of the previously retained testes compared to non-treatment. METHODS: At the age of 6 mo, 70 boys were randomized to surgical treatment at 9 mo and 79 boys to treatment at 3 y of age. The boys were then followed at 12 and 24 mo. Ultrasonography was used to determine testicular volume. RESULTS: After orchidopexy, the previously retained testes resumed growth and were significantly larger than the non-operated testes at 2 y (0.49 ml vs 0.36 ml, p<0.001). Testicular growth after orchidopexy was also demonstrated by a higher mean ratio between the previously retained and the scrotal testes of the individual boys at 2 y: 0.84 for the surgically treated group, compared to 0.63 for the untreated group (p<0.001). CONCLUSION: Surgery at 9 mo has a beneficial effect on the growth of previously undescended testes.
Authors: Julia S Barthold; Yanping Wang; Thomas F Kolon; Claude Kollin; Agneta Nordenskjöld; Alicia Olivant Fisher; T Ernesto Figueroa; Ahmad H BaniHani; Jennifer A Hagerty; Ricardo Gonzalez; Paul H Noh; Rosetta M Chiavacci; Kisha R Harden; Debra J Abrams; Cecilia E Kim; Abigail B Mateson; Alan K Robbins; Jin Li; Robert E Akins; Hakon Hakonarson; Marcella Devoto Journal: J Urol Date: 2014-10-25 Impact factor: 7.450
Authors: Julia Spencer Barthold; Yanping Wang; Thomas F Kolon; Claude Kollin; Agneta Nordenskjöld; Alicia Olivant Fisher; T Ernesto Figueroa; Ahmad H BaniHani; Jennifer A Hagerty; Ricardo Gonzaléz; Paul H Noh; Rosetta M Chiavacci; Kisha R Harden; Debra J Abrams; Cecilia E Kim; Jin Li; Hakon Hakonarson; Marcella Devoto Journal: Hum Reprod Date: 2015-07-24 Impact factor: 6.918
Authors: Georg Hrivatakis; Wolfgang Astfalk; Andreas Schmidt; Andreas Hartwig; Thomas Kugler; Thomas Heim; Axel Clausner; Albrecht Frunder; Harduin Weber; Steffan Loff; Joerg Fuchs; Verena Ellerkamp Journal: Dtsch Arztebl Int Date: 2014-09-26 Impact factor: 5.594