Melinda Y Yeung1. 1. Department of Pharmacy, The Children's Hospital at Westmead, New South Wales, Australia. melinday@chw.edu.au
Abstract
UNLABELLED: Intrauterine growth retardation is associated with oligonephropathy and the risk of hypertension and renal disease in adulthood. Animal study data show that nephron density is directly related to protein nutrition status during nephrogenesis. Among infants born at low gestation, postnatal growth retardation and major deficits in energy and protein intake have been reported. CONCLUSION: Since nephrogenesis occurs mainly in late gestation, increasing protein intake during nephrogenesis could minimize the risk of long-term morbidities associated with oligonephropathy.
UNLABELLED: Intrauterine growth retardation is associated with oligonephropathy and the risk of hypertension and renal disease in adulthood. Animal study data show that nephron density is directly related to protein nutrition status during nephrogenesis. Among infants born at low gestation, postnatal growth retardation and major deficits in energy and protein intake have been reported. CONCLUSION: Since nephrogenesis occurs mainly in late gestation, increasing protein intake during nephrogenesis could minimize the risk of long-term morbidities associated with oligonephropathy.
Authors: Mary Y Sun; Joseph C Woolley; Sharon E Blohowiak; Zachary R Smith; Ashajyothi M Siddappa; Ronald R Magness; Pamela J Kling Journal: Reprod Fertil Dev Date: 2016-02-15 Impact factor: 2.311
Authors: Hanneke Bakker; Romy Gaillard; Oscar H Franco; Albert Hofman; Albert J van der Heijden; Eric A P Steegers; H Rob Taal; Vincent W V Jaddoe Journal: J Am Soc Nephrol Date: 2014-05-08 Impact factor: 10.121