F S Weinand1, F Althen. 1. Department of Ophthalmology, University Eye Clinic, Giessen, Germany. Frank.S.Weinand@augen.med.uni-giessen.de
Abstract
PURPOSE: To investigate the long-term efficacy of selective laser trabeculoplasty (SLT) in primary open-angle glaucoma, the authors performed a non-randomized, prospective, non-comparative clinical case series. METHODS: Fifty-two eyes of 52 patients (19 male, 33 female) with primary open angle glaucoma were treated with SLT. Patients were treated with the Coherent Selecta 7000 (Coherent, Palo Alto, CA, USA) frequency-doubled q-switched Nd:YAG laser (532 nm). A total of approximately 50 non-overlapping spots were placed over 180 degrees of the trabecular meshwork at energy levels ranging from 0.6 to 1.4 mJ per pulse. After surgery, patients were maintained with the drug regimen identical to that before treatment. RESULTS: After 1 year the average reduction in intraocular pressure (IOP) from the baseline was 24.3% (6.0 mmHg), after 2 years 27.8% (6.12 mmHg), after 3 years 24.5% (5.53 mmHg), and after 4 years 29.3% (6.33 mmHg). A Kaplan-Meier survival analysis revealed a 1-year success rate of 60%, a 2-year success rate of 53%, a 3-year success rate of 44%, and a 4-year success rate of 44%. CONCLUSIONS: Despite a declining success rate, SLT is an effective method to lower IOP over an extended period of time.
PURPOSE: To investigate the long-term efficacy of selective laser trabeculoplasty (SLT) in primary open-angle glaucoma, the authors performed a non-randomized, prospective, non-comparative clinical case series. METHODS: Fifty-two eyes of 52 patients (19 male, 33 female) with primary open angle glaucoma were treated with SLT. Patients were treated with the Coherent Selecta 7000 (Coherent, Palo Alto, CA, USA) frequency-doubled q-switched Nd:YAG laser (532 nm). A total of approximately 50 non-overlapping spots were placed over 180 degrees of the trabecular meshwork at energy levels ranging from 0.6 to 1.4 mJ per pulse. After surgery, patients were maintained with the drug regimen identical to that before treatment. RESULTS: After 1 year the average reduction in intraocular pressure (IOP) from the baseline was 24.3% (6.0 mmHg), after 2 years 27.8% (6.12 mmHg), after 3 years 24.5% (5.53 mmHg), and after 4 years 29.3% (6.33 mmHg). A Kaplan-Meier survival analysis revealed a 1-year success rate of 60%, a 2-year success rate of 53%, a 3-year success rate of 44%, and a 4-year success rate of 44%. CONCLUSIONS: Despite a declining success rate, SLT is an effective method to lower IOP over an extended period of time.
Authors: Sylvia L Groth; Eiyass Albeiruti; Mariana Nunez; Roman Fajardo; Lucie Sharpsten; Nils Loewen; Joel S Schuman; Jeffrey L Goldberg Journal: Ophthalmology Date: 2019-06-06 Impact factor: 12.079
Authors: Varun Patel; Eman El Hawy; Michael Waisbourd; Camila Zangalli; Daniel M Shapiro; Lalita Gupta; Michael Hsieh; Abigail Kasprenski; L Jay Katz; George L Spaeth Journal: Int J Ophthalmol Date: 2015-10-18 Impact factor: 1.779