Literature DB >> 1649620

Characterisation of palygorskite specimens from different geological locales for health hazard evaluation.

R P Nolan1, A M Langer, G B Herson.   

Abstract

Palygorskite, a fibrous clay mineral, is being used as a substitute for asbestos in some applications. Nine specimens obtained from different geological locales were studied for mineral purity, elemental composition, fibre size distribution, and surface binding characteristics. The membranolytic activity of each was determined using a human erythrocyte model. The membranolytic behaviour and surface binding characteristics were compared with three chrysotile specimens employed as positive controls. The palygorskite specimens derived from the different geological locales display a range of physicochemical properties. This study shows the importance of selecting several mineral specimens for a health hazard evaluation. The current carcinogenic classification of the mineral may be limited due to the number of specimens used for that particular evaluation.

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Year:  1991        PMID: 1649620      PMCID: PMC1035399          DOI: 10.1136/oem.48.7.463

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN: 0007-1072


  19 in total

1.  Pleural carcinogenic potency of mineral fibers (asbestos, attapulgite) and their cytotoxicity on cultured cells.

Authors:  M C Jaurand; J Fleury; G Monchaux; M Nebut; J Bignon
Journal:  J Natl Cancer Inst       Date:  1987-10       Impact factor: 13.506

2.  Potential health risks from the use of fibrous mineral absorption granulates.

Authors:  K Rödelsperger; B Brückel; J Manke; H J Woitowitz; F Pott
Journal:  Br J Ind Med       Date:  1987-05

3.  Asbestos hemolysis.

Authors:  R J Schnitzer; F L Pundsack
Journal:  Environ Res       Date:  1970-01       Impact factor: 6.498

4.  Experimental studies with palygorskite dusts.

Authors:  J C Wagner; D M Griffiths; D E Munday
Journal:  Br J Ind Med       Date:  1987-11

5.  Early changes in the pleural mesothelium following intrapleural inoculation of the mineral fibre erionite and the subsequent development of mesotheliomas.

Authors:  R J Hill; R E Edwards; P Carthew
Journal:  J Exp Pathol (Oxford)       Date:  1990-02

Review 6.  Mineral fibre carcinogenesis: experimental data relating to the importance of fibre type, size, deposition, dissolution and migration.

Authors:  J M Davis
Journal:  IARC Sci Publ       Date:  1989

Review 7.  Review of the significance of fibre size in fibre-related lung disease: a centrifuge cell for preparing accurate microscope-evaluation specimens from slurries used in inoculation studies.

Authors:  V Timbrell
Journal:  Ann Occup Hyg       Date:  1989

8.  Carcinogenicity studies on fibres, metal compounds, and some other dusts in rats.

Authors:  F Pott; U Ziem; F J Reiffer; F Huth; H Ernst; U Mohr
Journal:  Exp Pathol       Date:  1987

9.  Interactions of attapulgite (fibrous clay) with human red blood cells.

Authors:  M Perderiset; L S Etienne; J Bignon; M C Jaurand
Journal:  Toxicol Lett       Date:  1989-06       Impact factor: 4.372

10.  Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats.

Authors:  S Okada; S Hamazaki; S Toyokuni; O Midorikawa
Journal:  Br J Cancer       Date:  1989-11       Impact factor: 7.640

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