Literature DB >> 16496113

[Mental neuropathy and pathologic fracture of the mandible as initial symptoms of metastatic prostate carcinoma].

J Polligkeit1, C Westendorff, S M Kröber, M Zerfowski, J Hoffmann.   

Abstract

BACKGROUND: Distant metastases of solid tumors account for about 1% of all malign neoplasms. In about 30% of all patients who present with an oral metastasis, the distant primary tumour has not been diagnosed yet. CASE REPORT: We report the case of a 71-year-old man who clinically demonstrated unilateral mental neuropathy as well as pathologic fracture of the mandible. Prostate carcinoma was identified as a primary tumor. Clinically, there was significant hypesthesia of the skin area innervated by the left inferior alveolar nerve. X-ray examination revealed an osteolytic lesion of the ascending ramus of the mandible as well as a pathologic fracture of the mandible. Further imaging showed an extensive neoplasm of the mandible and adjacent soft tissues and significant supraclavicular lymph node enlargement. The diagnosis of metastatic carcinoma of the prostate was histopathologically confirmed.
CONCLUSION: Mental neuropathy without a dental focus indicates screening for an osseous metastasis. In cases of left-sided supraclavicular lymph node enlargement in men over 45 years, metastatic prostate carcinoma must be excluded.

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Year:  2006        PMID: 16496113     DOI: 10.1007/s10006-006-0672-6

Source DB:  PubMed          Journal:  Mund Kiefer Gesichtschir        ISSN: 1432-9417


  17 in total

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Journal:  Surg Clin North Am       Date:  1962-06       Impact factor: 2.741

2.  Enlargement of the supraclavicular lymph nodes as the initial sign of prostatic carcinoma.

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Review 4.  Condylar metastasis: a review and case report.

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Journal:  Br J Oral Maxillofac Surg       Date:  1994-06       Impact factor: 1.651

5.  Mental neuropathy: report of five cases and review of the literature.

Authors:  F M Laurencet; S Anchisi; E Tullen; P Y Dietrich
Journal:  Crit Rev Oncol Hematol       Date:  2000-04       Impact factor: 6.312

6.  Numb chin syndrome as the presenting symptom of metastatic prostate carcinoma.

Authors:  S Halachmi; R Madeb; S Madjar; M Wald; Y River; O Nativ
Journal:  Urology       Date:  2000-02       Impact factor: 2.649

7.  Immunohistochemical localization of prostate-specific acid phosphatase and prostate-specific antigen in stage A2 adenocarcinoma of the prostate: prognostic implications.

Authors:  J I Epstein; J C Eggleston
Journal:  Hum Pathol       Date:  1984-09       Impact factor: 3.466

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Journal:  J Oral Surg       Date:  1979-11

Review 9.  Malignant tumors of the oral cavity and oropharynx: clinical, pathologic, and radiologic evaluation.

Authors:  Alfred L Weber; Laura Romo; Sadaf Hashmi
Journal:  Neuroimaging Clin N Am       Date:  2003-08       Impact factor: 2.264

10.  Metastatic prostatic carcinoma to supradiaphragmatic lymph nodes. A clinicopathologic and immunohistochemical study.

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Journal:  Am J Surg Pathol       Date:  1987-06       Impact factor: 6.394

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  1 in total

1.  Hyperglobus, do not forget the sinister.

Authors:  Aitor de Gea Rico; Sat Parmar; Peter J Revington
Journal:  BMJ Case Rep       Date:  2012-09-03
  1 in total

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