Literature DB >> 16495279

Roles of cellular respiration, CgCDR1, and CgCDR2 in Candida glabrata resistance to histatin 5.

Eva J Helmerhorst1, Caterina Venuleo, Dominique Sanglard, Frank G Oppenheim.   

Abstract

Histatin 5, a human salivary protein with broad-spectrum antifungal activity, is remarkably ineffective against Candida glabrata. Fluconazole resistance in this fungus is due in most cases to upregulation of CgCDR efflux pumps. We investigated whether the distinct resistance of C. glabrata to histatin 5 is related to similar mechanisms.

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Year:  2006        PMID： 16495279      PMCID： PMC1426449          DOI： 10.1128/AAC.50.3.1100-1103.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

Review 1.  Salivary histatin 5 and its similarities to the other antimicrobial proteins in human saliva.

Authors:  M Edgerton; S E Koshlukova
Journal:  Adv Dent Res       Date:  2000-12

2.  Candida albicans mutants deficient in respiration are resistant to the small cationic salivary antimicrobial peptide histatin 5.

Authors:  C Gyurko; U Lendenmann; R F Troxler; F G Oppenheim
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

3.  Transient-state analysis of metabolic fluxes in crabtree-positive and crabtree-negative yeasts.

Authors:  H Van Urk; W S Voll; W A Scheffers; J P Van Dijken
Journal:  Appl Environ Microbiol       Date:  1990-01       Impact factor: 4.792

4.  Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.

Authors:  D Sanglard; F Ischer; J Bille
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

5.  Respiration of medically important Candida species and Saccharomyces cerevisiae in relation to glucose effect.

Authors:  M Niimi; A Kamiyama; M Tokunaga
Journal:  J Med Vet Mycol       Date:  1988-06

6.  In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata.

Authors:  Alain Defontaine; Jean-Philippe Bouchara; Philippe Declerk; Claire Planchenault; Dominique Chabasse; Jean-Noel Hallet
Journal:  J Med Microbiol       Date:  1999-07       Impact factor: 2.472

7.  The concomitant expression and availability of conventional and alternative, cyanide-insensitive, respiratory pathways in Candida albicans.

Authors:  Eva J Helmerhorst; Maria Stan; Michael P Murphy; Fred Sherman; Frank G Oppenheim
Journal:  Mitochondrion       Date:  2005-06       Impact factor: 4.160

8.  Released ATP is an extracellular cytotoxic mediator in salivary histatin 5-induced killing of Candida albicans.

Authors:  S E Koshlukova; M W Araujo; D Baev; M Edgerton
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

9.  In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole.

Authors:  Guo-Xian Wei; Libuse A Bobek
Journal:  J Antimicrob Chemother       Date:  2004-04-08       Impact factor: 5.790

10.  Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis.

Authors:  John E Bennett; Koichi Izumikawa; Kieren A Marr
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191
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  9 in total

1.  Antifungal Activity of the Noncytotoxic Human Peptide Hepcidin 20 against Fluconazole-Resistant Candida glabrata in Human Vaginal Fluid.

Authors:  Gaetano Del Gaudio; Lisa Lombardi; Giuseppantonio Maisetta; Semih Esin; Giovanna Batoni; Maurizio Sanguinetti; Sonia Senesi; Arianna Tavanti
Journal:  Antimicrob Agents Chemother       Date:  2013-06-24       Impact factor: 5.191

2.  Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans.

Authors:  Hyeseung Lee; Ami Khanal Lamichhane; H Martin Garraffo; Kyung J Kwon-Chung; Yun C Chang
Journal:  Mol Microbiol       Date:  2012-03-15       Impact factor: 3.501

3.  Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes.

Authors:  Edward Sionov; Hyeseung Lee; Yun C Chang; Kyung J Kwon-Chung
Journal:  PLoS Pathog       Date:  2010-04-01       Impact factor: 6.823

Review 4.  Antimicrobial peptides: primeval molecules or future drugs?

Authors:  Brian M Peters; Mark E Shirtliff; Mary Ann Jabra-Rizk
Journal:  PLoS Pathog       Date:  2010-10-28       Impact factor: 6.823

5.  Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.

Authors:  Edward Sionov; Yun C Chang; H Martin Garraffo; Kyung J Kwon-Chung
Journal:  Antimicrob Agents Chemother       Date:  2009-05-04       Impact factor: 5.191

Review 6.  Candida glabrata: a review of its features and resistance.

Authors:  C F Rodrigues; S Silva; M Henriques
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-11-19       Impact factor: 3.267

7.  Histatin 5 resistance of Candida glabrata can be reversed by insertion of Candida albicans polyamine transporter-encoding genes DUR3 and DUR31.

Authors:  Swetha Tati; Woong Sik Jang; Rui Li; Rohitashw Kumar; Sumant Puri; Mira Edgerton
Journal:  PLoS One       Date:  2013-04-22       Impact factor: 3.240

Review 8.  Efflux in fungi: la pièce de résistance.

Authors:  Jeffrey J Coleman; Eleftherios Mylonakis
Journal:  PLoS Pathog       Date:  2009-06-26       Impact factor: 6.823

Review 9.  Candida glabrata Biofilms: How Far Have We Come?

Authors:  Célia F Rodrigues; Maria Elisa Rodrigues; Sónia Silva; Mariana Henriques
Journal:  J Fungi (Basel)       Date:  2017-03-01
  9 in total

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