Literature DB >> 16494494

A highly enantioselective lewis basic organocatalyst for reduction of N-aryl imines with unprecedented substrate spectrum.

Zhouyu Wang1, Xiaoxia Ye, Siyu Wei, Pengcheng Wu, Anjiang Zhang, Jian Sun.   

Abstract

L-Pipecolinic acid derived formamides have been developed as highly efficient and enantioselective Lewis basic organocatalysts for the reduction of N-aryl imines with trichlorosilane. Catalyst 4b afforded high isolated yields (up to 98%) and enantioselectivities (up to 96%) under mild conditions with an unprecedented substrate spectrum.

Entities:  

Year:  2006        PMID： 16494494     DOI： 10.1021/ol060112g

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Highly efficient diastereoselective reduction of alpha-fluoroimines.

Authors:  Roy M Malamakal; Whitney R Hess; Todd A Davis
Journal:  Org Lett       Date:  2010-05-21       Impact factor: 6.005

2.  Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts.

Authors:  Bhaskar C Das; Seetaram Mohapatra; Philip D Campbell; Sabita Nayak; Sakkarapalayam M Mahalingam; Todd Evans
Journal:  Tetrahedron Lett       Date:  2010-05-01       Impact factor: 2.415

3.  Combinatorial synthesis of chemical building blocks 1. Azomethines.

Authors:  Sergey V Ryabukhin; Dmitriy M Panov; Andrey S Plaskon; Alexander Chuprina; Sergey E Pipko; Andrey A Tolmachev; Alexander N Shivanyuk
Journal:  Mol Divers       Date:  2012-10-30       Impact factor: 2.943

4.  Enantioselective reduction of ketoimines promoted by easily available (S)-proline derivatives.

Authors:  Martina Bonsignore; Maurizio Benaglia; Laura Raimondi; Manuel Orlandi; Giuseppe Celentano
Journal:  Beilstein J Org Chem       Date:  2013-04-02       Impact factor: 2.883
  4 in total

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