| Literature DB >> 16494457 |
Shashank Shekhar1, Per Ryberg, John F Hartwig.
Abstract
The rates of oxidative addition of phenyl bromide to [Pd(BINAP)2] have been measured in the presence and absence of added amine to assess a previous hypothesis that addition to [Pd(BINAP)(amine)] is faster than addition to [Pd(BINAP)]. These data show that addition to the amine complex is not faster than addition to [Pd(BINAP)]. Instead, they are consistent with oxidative addition, even in the presence of amine, to [Pd(BINAP)] as the major pathway. These data underscore the value of studying the stoichiometric reactions of isolated complexes when assessing the mechanism of a catalytic process.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16494457 DOI： 10.1021/ol0528890
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005