Literature DB >> 16494452

A short total synthesis of (+/-)-aspidospermidine.

Lisa A Sharp1, Samir Z Zard.   

Abstract

A cascade radical cyclization starting from an amidyl radical has been used for the construction of (+/-)-aspidospermidine. This approach has also been developed for the preparation of a tricycle whose framework is contained in the stemona alkaloids.

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Year:  2006        PMID： 16494452     DOI： 10.1021/ol052749q

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Synthetic and Computational Study of Tin-Free Reductive Tandem Cyclizations of Neutral Aminyl Radicals.

Authors:  Hansamali S Sirinimal; Sebastien P Hebert; Ganesh Samala; Heng Chen; Gregory J Rosenhauer; H Bernhard Schlegel; Jennifer L Stockdill
Journal:  Org Lett       Date:  2018-09-28       Impact factor: 6.005

Review 2.  Some aspects of radical cascade and relay reactions.

Authors:  Béatrice Quiclet-Sire; Samir Z Zard
Journal:  Proc Math Phys Eng Sci       Date:  2017-04-05       Impact factor: 2.704

3.  Intramolecular anodic olefin coupling reactions: using competition studies to probe the mechanism of oxidative cyclization reactions.

Authors:  Hai-Chao Xu; Kevin D Moeller
Journal:  Org Lett       Date:  2010-04-16       Impact factor: 6.005

4.  Concise and enantioselective total synthesis of (-)-mehranine, (-)-methylenebismehranine, and related Aspidosperma alkaloids.

Authors:  Marius Mewald; Jonathan William Medley; Mohammad Movassaghi
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-04       Impact factor: 15.336

5.  Pyrrolidine and piperidine formation via copper(II) carboxylate-promoted intramolecular carboamination of unactivated olefins: diastereoselectivity and mechanism.

Authors:  Eric S Sherman; Peter H Fuller; Dhanalakshmi Kasi; Sherry R Chemler
Journal:  J Org Chem       Date:  2007-04-12       Impact factor: 4.354

6.  Visible-Light-Mediated Generation of Nitrogen-Centered Radicals: Metal-Free Hydroimination and Iminohydroxylation Cyclization Reactions.

Authors:  Jacob Davies; Samuel G Booth; Stephanie Essafi; Robert A W Dryfe; Daniele Leonori
Journal:  Angew Chem Int Ed Engl       Date:  2015-09-28       Impact factor: 15.336

7.  A Route to the C,D,E Ring System of the Aspidosperma Alkaloids.

Authors:  Geoffrey M Giampa; Jian Fang; Matthias Brewer
Journal:  Org Lett       Date:  2016-08-08       Impact factor: 6.005
  7 in total

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