Literature DB >> 16493418

Complex networks orchestrate epithelial-mesenchymal transitions.

Jean Paul Thiery1, Jonathan P Sleeman.   

Abstract

Epithelial-mesenchymal transition is an indispensable mechanism during morphogenesis, as without mesenchymal cells, tissues and organs will never be formed. However, epithelial-cell plasticity, coupled to the transient or permanent formation of mesenchyme, goes far beyond the problem of cell-lineage segregation. Understanding how mesenchymal cells arise from an epithelial default status will also have a strong impact in unravelling the mechanisms that control fibrosis and cancer progression.

Entities:  

Mesh:

Year:  2006        PMID: 16493418     DOI: 10.1038/nrm1835

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  1673 in total

Review 1.  The connectivity of lymphogenous and hematogenous tumor cell dissemination: biological insights and clinical implications.

Authors:  Jonathan P Sleeman; Blake Cady; Klaus Pantel
Journal:  Clin Exp Metastasis       Date:  2012-06-06       Impact factor: 5.150

2.  Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

Authors:  Toshiyuki Tsunoda; Yasuo Takashima; Takahiro Fujimoto; Midori Koyanagi; Yasuhiro Yoshida; Keiko Doi; Yoko Tanaka; Masahide Kuroki; Takehiko Sasazuki; Senji Shirasawa
Journal:  Neoplasia       Date:  2010-05       Impact factor: 5.715

3.  Loss of BRMS1 promotes a mesenchymal phenotype through NF-κB-dependent regulation of Twist1.

Authors:  Yuan Liu; Marty W Mayo; Aizhen Xiao; Emily H Hall; Elianna B Amin; Kyuichi Kadota; Prasad S Adusumilli; David R Jones
Journal:  Mol Cell Biol       Date:  2014-11-03       Impact factor: 4.272

4.  Implication of Bcl-2-associated athanogene 3 in fibroblast growth factor-2-mediated epithelial-mesenchymal transition in renal epithelial cells.

Authors:  Feng Du; Si Li; Tian Wang; Hai-Yan Zhang; De-Tian Li; Zhen-Xian Du; Hua-Qin Wang
Journal:  Exp Biol Med (Maywood)       Date:  2014-10-30

5.  HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells.

Authors:  Sugiko Watanabe; Yasuaki Ueda; Shin-ichi Akaboshi; Yuko Hino; Yoko Sekita; Mitsuyoshi Nakao
Journal:  Am J Pathol       Date:  2009-01-29       Impact factor: 4.307

6.  The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition.

Authors:  Larisa V Fedorova; Vanamala Raju; Nasser El-Okdi; Amjad Shidyak; David J Kennedy; Sandeep Vetteth; David R Giovannucci; Alexei Y Bagrov; Olga V Fedorova; Joseph I Shapiro; Deepak Malhotra
Journal:  Am J Physiol Renal Physiol       Date:  2009-01-28

7.  ZEB-1, a repressor of the semaphorin 3F tumor suppressor gene in lung cancer cells.

Authors:  Jonathan Clarhaut; Robert M Gemmill; Vincent A Potiron; Slimane Ait-Si-Ali; Jean Imbert; Harry A Drabkin; Joëlle Roche
Journal:  Neoplasia       Date:  2009-02       Impact factor: 5.715

8.  Insights into the epithelial mesenchymal transition phenotype in cancer of unknown primary from a global microRNA profiling study.

Authors:  A Stoyianni; G Pentheroudakis; H Benjamin; A Cervantes; K Ashkenazi; G Lazaridis; N Pavlidis; Y Spector
Journal:  Clin Transl Oncol       Date:  2013-11-27       Impact factor: 3.405

9.  Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition.

Authors:  Eva M Rico-Leo; Alberto Alvarez-Barrientos; Pedro M Fernandez-Salguero
Journal:  J Biol Chem       Date:  2013-02-04       Impact factor: 5.157

10.  Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer.

Authors:  Yin-Ju Chen; Chia-Chun Kuo; Lai-Lei Ting; Long-Sheng Lu; Ya-Ching Lu; Ann-Joy Cheng; Yun-Tien Lin; Chien-Ho Chen; Jo-Ting Tsai; Jeng-Fong Chiou
Journal:  Oncol Lett       Date:  2017-11-24       Impact factor: 2.967

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.