| Literature DB >> 16492535 |
E O Ajaiyeoba1, O O Abiodun, M O Falade, N O Ogbole, J S Ashidi, C T Happi, D O Akinboye.
Abstract
Twenty plants identified and selected from Southwest and Middle belt Nigerian antimalarial ethnopharmacology were evaluated for in vitro cytotoxicity using the brine shrimp lethality assay. The methanol extracts of 20 plant samples from 11 plant families were subjected to the assay. Of the studied plants, Lippia multiflora and Morinda lucida bark were found to be cytotoxic, with LC(50) values of 1.1 and 2.6 microg/ml, respectively. The least toxic plant extract was Bridelia micrantha (LC(50) value >9.0 x 10(6) microg/ml). Most of the plants were found to be relatively non-toxic.Entities:
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Year: 2005 PMID： 16492535 DOI： 10.1016/j.phymed.2005.01.015
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340