Literature DB >> 164924

Studies on the interaction between heparin and mouse bone collagenase.

S Sakamoto, M Sakamoto, P Goldhaber, M J Glimcher.   

Abstract

Mouse bone collagenase was found to be tightly bound to a heparin-substituted gel at low ionic strength. The bond was reversible, however, and the collagenase could be elutted at high ionic strength. In addition to providing a method for purifying the enzyme with high yield, the results suggest that the strong ionic bond between heparin and collagenase may partially explain the mechanism wherein heparin enhances the activity of mouse bone collagenase.

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Year:  1975        PMID： 164924     DOI： 10.1016/0304-4165(75)90072-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen.

Authors:  G Vaes; Y Eeckhout; G Lenaers-Claeys; C François-Gillet; J E Druetz
Journal:  Biochem J       Date:  1978-05-15       Impact factor: 3.857

Review 2.  Peripheral membrane associations of matrix metalloproteinases.

Authors:  Steven R Van Doren; Tara C Marcink; Rama K Koppisetti; Alexander Jurkevich; Yan G Fulcher
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2017-04-23       Impact factor: 4.739

3.  Purification and characterization of a collagenase extracted from rabbit tumours.

Authors:  P A McCroskery; J F Richards; E D Harris
Journal:  Biochem J       Date:  1975-10       Impact factor: 3.857

4.  Heparin-binding fragments of fibronectin are potent inhibitors of endothelial cell growth.

Authors:  G A Homandberg; J E Williams; D Grant; B Schumacher; R Eisenstein
Journal:  Am J Pathol       Date:  1985-09       Impact factor: 4.307

5.  Purification of pig synovial collagenase to high specific activity.

Authors:  T E Cawston; J A Tyler
Journal:  Biochem J       Date:  1979-12-01       Impact factor: 3.857

6.  Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice.

Authors:  W Zhao; M H Byrne; B F Boyce; S M Krane
Journal:  J Clin Invest       Date:  1999-02       Impact factor: 14.808

7.  Mast cells at sites of cartilage erosion in the rheumatoid joint.

Authors:  M Bromley; W D Fisher; D E Woolley
Journal:  Ann Rheum Dis       Date:  1984-02       Impact factor: 19.103

8.  Collagenase and collagenase inhibitors in osteoarthritic and normal cartilage.

Authors:  M G Ehrlich; H J Mankin; H Jones; R Wright; C Crispen; G Vigliani
Journal:  J Clin Invest       Date:  1977-02       Impact factor: 14.808

9.  Angiogenesis inhibitors and their delivery systems.

Authors:  R Langer; J Murray
Journal:  Appl Biochem Biotechnol       Date:  1983-02       Impact factor: 2.926
  9 in total

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