| Literature DB >> 16492376 |
Abstract
Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".Entities:
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Year: 2006 PMID： 16492376 PMCID： PMC2689307 DOI： 10.1186/1297-9686-38-2-221
Source DB: PubMed Journal: Genet Sel Evol ISSN： 0999-193X Impact factor: 4.297