BACKGROUND: Approximately one quarter of the acute ischemic stroke patients notice the event at awakening. Such patients with stroke at awakening are usually excluded from thrombolysis, since the time of stroke onset cannot be definitely identified. We compared the hyperacute CT findings of awakening stroke patients with those of stroke patients with known onset to assess whether the time of stroke onset is shortly before awakening. METHODS: Subjects were cardioembolic stroke patients who were consecutively admitted to our department within 3 h after the recognition of stroke during the period between January 2000 and March 2003. The patients were classified into three groups: group A with stroke of known onset, group B with stroke at awakening, and group C with stroke of unknown onset due to lack of a witness. The clinical and CT findings in each group were compared. RESULTS: A total of 81 patients fulfilled the study criteria. There were 46 patients in group A, 17 patients in group B, and 18 patients in group C. There was no significant difference in CT findings between groups A and B. In group C, however, definite hypodense areas were more commonly found than in group A (56 vs. 0%; p<0.001) or in group B (56 vs. 11%; p=0.012). CONCLUSION: Based on our CT findings, stroke at awakening seems to be developing shortly before in a large subset of patients, making them potential candidates for acute stroke therapies. Copyright (c) 2006 S. Karger AG, Basel.
BACKGROUND: Approximately one quarter of the acute ischemic strokepatients notice the event at awakening. Such patients with stroke at awakening are usually excluded from thrombolysis, since the time of stroke onset cannot be definitely identified. We compared the hyperacute CT findings of awakening strokepatients with those of strokepatients with known onset to assess whether the time of stroke onset is shortly before awakening. METHODS: Subjects were cardioembolic strokepatients who were consecutively admitted to our department within 3 h after the recognition of stroke during the period between January 2000 and March 2003. The patients were classified into three groups: group A with stroke of known onset, group B with stroke at awakening, and group C with stroke of unknown onset due to lack of a witness. The clinical and CT findings in each group were compared. RESULTS: A total of 81 patients fulfilled the study criteria. There were 46 patients in group A, 17 patients in group B, and 18 patients in group C. There was no significant difference in CT findings between groups A and B. In group C, however, definite hypodense areas were more commonly found than in group A (56 vs. 0%; p<0.001) or in group B (56 vs. 11%; p=0.012). CONCLUSION: Based on our CT findings, stroke at awakening seems to be developing shortly before in a large subset of patients, making them potential candidates for acute stroke therapies. Copyright (c) 2006 S. Karger AG, Basel.
Authors: Lee H Schwamm; Ona Wu; Shlee S Song; Lawrence L Latour; Andria L Ford; Amie W Hsia; Alona Muzikansky; Rebecca A Betensky; Albert J Yoo; Michael H Lev; Gregoire Boulouis; Arne Lauer; Pedro Cougo; William A Copen; Gordon J Harris; Steven Warach Journal: Ann Neurol Date: 2018-04-27 Impact factor: 10.422
Authors: Shlee S Song; Lawrence L Latour; Carsten H Ritter; Ona Wu; Mourad Tighiouart; Daymara A Hernandez; Katherine D Ku; Marie Luby; Steven Warach Journal: Stroke Date: 2012-06-12 Impact factor: 7.914
Authors: Andrew D Barreto; Sheryl Martin-Schild; Hen Hallevi; Miriam M Morales; Anitha T Abraham; Nicole R Gonzales; Kachi Illoh; James C Grotta; Sean I Savitz Journal: Stroke Date: 2009-01-08 Impact factor: 7.914
Authors: Jan W Dankbaar; Henri P Bienfait; Coen van den Berg; Edwin Bennink; Alexander D Horsch; Tom van Seeters; Irene C van der Schaaf; L Jaap Kappelle; Birgitta K Velthuis Journal: Cerebrovasc Dis Date: 2018-05-17 Impact factor: 2.762