Literature DB >> 16489334

Formation of human prostate tissue from embryonic stem cells.

Renea A Taylor1, Prue A Cowin, Gerald R Cunha, Martin Pera, Alan O Trounson, John Pedersen, Gail P Risbridger.   

Abstract

Rodent models and immortalized or genetically modified cell lines are frequently used-but have limited utility-for studying human prostate development and maturation. Using rodent mesenchyme to establish reciprocal mesenchymal-epithelial cell interactions with human embryonic stem cells (hESCs), we generated human prostate tissue expressing prostate-specific antigen (PSA) within 8-12 weeks. This human prostate model shows species-conserved signalling mechanisms that could extend to integumental, gastrointestinal and genital tissues.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16489334     DOI： 10.1038/nmeth855

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  42 in total

1.  Stem Cells as Hormone Targets That Lead to Increased Cancer Susceptibility.

Authors:  Gail S Prins; Esther L Calderon-Gierszal; Wen-Yang Hu
Journal:  Endocrinology       Date:  2015-08-04       Impact factor: 4.736

2.  Prostate cancer: Novel xenografts in mice--a new wave of preclinical models.

Authors:  Gail P Risbridger
Journal:  Nat Rev Urol       Date:  2015-08-18       Impact factor: 14.432

3.  The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells.

Authors:  Donald J Vander Griend; Wouter L Karthaus; Susan Dalrymple; Alan Meeker; Angelo M DeMarzo; John T Isaacs
Journal:  Cancer Res       Date:  2008-12-01       Impact factor: 12.701

4.  Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.

Authors:  Bobby Bhatia; Ming Jiang; Mahipal Suraneni; Lubna Patrawala; Mark Badeaux; Robin Schneider-Broussard; Asha S Multani; Collene R Jeter; Tammy Calhoun-Davis; Limei Hu; Jianhua Hu; Spiridon Tsavachidis; Wei Zhang; Sandy Chang; Simon W Hayward; Dean G Tang
Journal:  J Biol Chem       Date:  2008-07-28       Impact factor: 5.157

Review 5.  Cellular and Molecular Mechanisms Underlying Prostate Cancer Development: Therapeutic Implications.

Authors:  Ugo Testa; Germana Castelli; Elvira Pelosi
Journal:  Medicines (Basel)       Date:  2019-07-30

6.  Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to Multispecies recombinant urogenital sinus xenografts.

Authors:  Donald J Vander Griend; Yuko Konishi; Angelo M De Marzo; John T Isaacs; Alan K Meeker
Journal:  Prostate       Date:  2009-10-01       Impact factor: 4.104

7.  Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells.

Authors:  Mitchell G Lawrence; Naira V Margaryan; Daniela Loessner; Angus Collins; Kris M Kerr; Megan Turner; Elisabeth A Seftor; Carson R Stephens; John Lai; Lynne-Marie Postovit; Judith A Clements; Mary J C Hendrix
Journal:  Prostate       Date:  2011-01-12       Impact factor: 4.104

Review 8.  Prostate epithelial stem and progenitor cells.

Authors:  Oh-Joon Kwon; Li Xin
Journal:  Am J Clin Exp Urol       Date:  2014-10-02

9.  Bladder expression of CD cell surface antigens and cell-type-specific transcriptomes.

Authors:  Alvin Y Liu; Ricardo Z N Vêncio; Laura S Page; Melissa E Ho; Michelle A Loprieno; Lawrence D True
Journal:  Cell Tissue Res       Date:  2012-03-20       Impact factor: 5.249

10.  Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling.

Authors:  Xiaohong Li; Yongqing Wang; Ali-Reza Sharif-Afshar; Consolate Uwamariya; Andrew Yi; Kenichiro Ishii; Simon W Hayward; Robert J Matusik; Neil A Bhowmick
Journal:  Differentiation       Date:  2008-10-25       Impact factor: 3.880
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.