Literature DB >> 1648929

Studies of the effect of acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats.

M A Sheets1, B A Unger, G F Giggleman, I R Tizard.   

Abstract

Feline leukemia is a disease induced by an oncornavirus infection that inevitably causes clinically affected cats to die. It has been estimated that 40% of cats are dead within 4 weeks and 70% within 8 weeks of the onset of clinical symptoms. Acemannan is a complex carbohydrate with both immunostimulatory and direct antiviral properties. Administration of acemannan for 6 weeks intraperitoneally to clinically symptomatic cats significantly improved both the quality of life and the survival rate. Twelve weeks after initiation of treatment, 71% of treated cats were alive and in good health.

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Year:  1991        PMID: 1648929

Source DB:  PubMed          Journal:  Mol Biother        ISSN: 0952-8172


  5 in total

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