| Literature DB >> 16488653 |
Vlada B Urlacher1, Rolf D Schmid.
Abstract
Oxygenases continue to be widely studied for selective biooxidation of organic compounds. Protein engineering has resulted in heme and flavin monooxygenases with widely altered substrate specificities, and attempts have been reported to scale-up reactions catalyzed by these enzymes. Cofactor regeneration is still a key issue in these developments. Protein engineering contributed to understanding of structure versus function in dioxygenases.Mesh:
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Year: 2006 PMID: 16488653 DOI: 10.1016/j.cbpa.2006.02.001
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN: 1367-5931 Impact factor: 8.822