OBJECTIVE: The aim of this study is to assess the clinical effectiveness of venous arterialization in patients with critical limb ischaemia not reconstructable by conventional bypass. DESIGN: Meta-analysis of observational studies. MATERIALS: Eligible studies concerning treatment by venous arterialization for chronic critical leg ischaemia were identified from electronic database, cross-reference search and pertinent articles. There was no language restriction. METHODS: All relevant studies were systematically reviewed and data extracted by two independent reviewers. Study endpoints were foot preservation, secondary graft patency, postoperative clinical improvement and complications. RESULTS: A total of 56 studies were selected for comprehensive review. No RCTs were identified. Seven patient series, comprising 228 patients, matched the selection criteria. Overall 1-year foot preservation was 71% (95% CI: 64-77%) and 1-year secondary patency was 46% (95% CI: 39-53%). The large majority of patients in whom major amputation was avoided experienced successful wound healing, disappearance of rest pain and absence of serious complications. CONCLUSION: On the basis of limited evidence, venous arterialization may be considered as a viable alternative before major amputation is undertaken in patients with 'inoperable' chronic critical leg ischaemia.
OBJECTIVE: The aim of this study is to assess the clinical effectiveness of venous arterialization in patients with critical limb ischaemia not reconstructable by conventional bypass. DESIGN: Meta-analysis of observational studies. MATERIALS: Eligible studies concerning treatment by venous arterialization for chronic critical leg ischaemia were identified from electronic database, cross-reference search and pertinent articles. There was no language restriction. METHODS: All relevant studies were systematically reviewed and data extracted by two independent reviewers. Study endpoints were foot preservation, secondary graft patency, postoperative clinical improvement and complications. RESULTS: A total of 56 studies were selected for comprehensive review. No RCTs were identified. Seven patient series, comprising 228 patients, matched the selection criteria. Overall 1-year foot preservation was 71% (95% CI: 64-77%) and 1-year secondary patency was 46% (95% CI: 39-53%). The large majority of patients in whom major amputation was avoided experienced successful wound healing, disappearance of rest pain and absence of serious complications. CONCLUSION: On the basis of limited evidence, venous arterialization may be considered as a viable alternative before major amputation is undertaken in patients with 'inoperable' chronic critical leg ischaemia.
Authors: Cesar Roberto Busato; Carlos Alberto Lima Utrabo; Leandro Cavalcante Lipinski; Marcelo de Oliveira Dreweck; Ana Carolina Viezzer Fernandes; Gabriel Sviercoski Journal: J Vasc Bras Date: 2020-07-31
Authors: Cesar Roberto Busato; Carlos Alberto Lima Utrabo; Leandro Cavalcante Lipinski; Mario Rodrigues Montemór; Eduardo de Souza Tolentino; Fernanda Aparecida de Oliveira Busato Nascimento; Marcio Dias Guilherme Journal: J Vasc Bras Date: 2016 Apr-Jun
Authors: Cesar Roberto Busato; Carlos Alberto Lima Utrabo; Leandro Cavalcante Lipinski; Keizi Dayane de Lima; Márcio Dias Guilherme; Nicolas Brandalize Medeiros; Samela Basi Fagundes; Willman Josviak Journal: J Vasc Bras Date: 2017 Jul-Sep