| Literature DB >> 16487697 |
Hugo Wurtele1, Alain Verreault.
Abstract
The packaging of DNA into chromatin creates a number of significant barriers to the detection of DNA lesions and their timely and accurate repair. Eukaryotic cells have evolved a number of enzymes that modulate chromatin structure and facilitate DNA repair. Recent research illustrates how nucleosome remodelling enzymes cooperate with both DNA-damage-inducible and constitutive histone modifications to promote many facets of the cellular response to DNA damage.Mesh：
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Year: 2006 PMID： 16487697 DOI： 10.1016/j.ceb.2006.02.008
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382