Literature DB >> 16485867

The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy.

Francesco Landi1, Andrea Russo, Matteo Cesari, Christian Barillaro, Graziano Onder, Valentina Zamboni, Antonello De Santis, Marco Pahor, Luigi Ferrucci, Roberto Bernabei.   

Abstract

BACKGROUND AND AIMS: "Invecchiamento e Longevità nel Sirente" (Aging and Longevity in the Sirente geographic area, ilSIRENTE) aims at investigating the socio-demographic, functional, clinical and biological characteristics of all subjects aged 80 years and older residing in a well-defined mountain area of Central Italy.
METHODS: Data are from the baseline evaluation of the ilSIRENTE prospective cohort study. A list of all persons living in the Sirente area was obtained from the Registry Offices of the 13 municipalities involved in the study. Data collection started in December 2003 and was completed in September 2004. Among the 429 residents older than 80 years eligible for the study, 364 accepted to participate (response rate 84%). Participants were assessed by trained staff who collected information on socio-demographic factors, clinical conditions, medication use, physical performance and muscle strength. All participants were also evaluated using the Minimum Data Set for Home Care (MDS-HC) form and a slightly modified version of the "Invecchiare in CHIANTI" study.
RESULTS: The mean age of participants was 85.6 +/- 4.8 years (range 80-102 years), with over 20% of participants aged 90 years or older. More than 65% of participants were women. Most participants (70%) were independent or required limited assistance in performing basic activities of daily living (ADL), whereas 30% of participants were independent in instrumental activities of daily living (IADL). Cognitive function (assessed by the Cognitive Performance Score) was normal in 80% of the sample. Higher degrees of disabilities (defined as the sum of dependencies in ADLs and IADLs) were associated with worse physical performance and lower muscle strength.
CONCLUSIONS: Data on the socio-demographic characteristics and health status of very old people living in the Sirente mountain community are discussed and compared with findings from other epidemiological studies.

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Year:  2005        PMID: 16485867     DOI: 10.1007/BF03327416

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  17 in total

1.  Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study.

Authors:  Graziano Onder; Rosa Liperoti; Andrea Russo; Ettore Capoluongo; Angelo Minucci; Paola Lulli; Matteo Cesari; Marcello Maggio; Roberto Bernabei; Francesco Landi
Journal:  Eur J Clin Pharmacol       Date:  2007-02-02       Impact factor: 2.953

2.  Impact of inappropriate drug use on physical performance among a frail elderly population living in the community.

Authors:  Francesco Landi; Andrea Russo; Rosa Liperoti; Christian Barillaro; Paola Danese; Marco Pahor; Roberto Bernabei; Graziano Onder
Journal:  Eur J Clin Pharmacol       Date:  2007-06-14       Impact factor: 2.953

3.  Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals.

Authors:  Silvia Giovannini; Graziano Onder; Rosa Liperoti; Andrea Russo; Christy Carter; Ettore Capoluongo; Marco Pahor; Roberto Bernabei; Francesco Landi
Journal:  J Am Geriatr Soc       Date:  2011-08-24       Impact factor: 5.562

4.  Functional impairment and risk of mortality in patients on chronic hemodialysis: results of the Lazio Dialysis Registry.

Authors:  Maurizio Bossola; Claudia Marino; Anteo Di Napoli; Nera Agabiti; Luigi Tazza; Marina Davoli
Journal:  J Nephrol       Date:  2018-03-23       Impact factor: 3.902

5.  Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community.

Authors:  A Russo; G Onder; M Cesari; V Zamboni; C Barillaro; E Capoluongo; M Pahor; R Bernabei; F Landi; L Ferrucci
Journal:  Occup Environ Med       Date:  2006-07       Impact factor: 4.402

6.  C-reactive protein and lipid parameters in older persons aged 80 years and older.

Authors:  M Cesari; G Onder; V Zamboni; E Capoluongo; A Russo; R Bernabei; M Pahor; F Landi
Journal:  J Nutr Health Aging       Date:  2009-08       Impact factor: 4.075

7.  Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community.

Authors:  Francesco Landi; Andrea Russo; Ettore Capoluongo; Matteo Cesari; Rosa Liperoti; Paola Danese; Roberto Bernabei; Graziano Onder
Journal:  Int J Hematol       Date:  2007-05       Impact factor: 2.490

8.  Physical function, physical activity and recent falls. Results from the "Invecchiamento e Longevità nel Sirente (ilSIRENTE)" Study.

Authors:  Irene Mangani; Matteo Cesari; Andrea Russo; Graziano Onder; Cinzia Maraldi; Valentina Zamboni; Niccolò Marchionni; Roberto Bernabei; Marco Pahor; Francesco Landi
Journal:  Aging Clin Exp Res       Date:  2008-06       Impact factor: 3.636

9.  Associations between a patient-reported outcome (PRO) measure of sarcopenia and falls, functional status, and physical performance in older patients with cancer.

Authors:  Jennifer S Gewandter; William Dale; Allison Magnuson; Chintan Pandya; Charles E Heckler; Tatyana Lemelman; Breton Roussel; Rafa Ifthikhar; James Dolan; Katia Noyes; Supriya G Mohile
Journal:  J Geriatr Oncol       Date:  2015-09-11       Impact factor: 3.599

10.  Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study.

Authors:  Francesco Landi; Rosa Liperoti; Andrea Russo; Silvia Giovannini; Matteo Tosato; Christian Barillaro; Ettore Capoluongo; Roberto Bernabei; Graziano Onder
Journal:  Eur J Nutr       Date:  2012-08-25       Impact factor: 5.614

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