Literature DB >> 16485422

Radiotherapy with laser-plasma accelerators: Monte Carlo simulation of dose deposited by an experimental quasimonoenergetic electron beam.

Y Glinec1, J Faure, V Malka, T Fuchs, H Szymanowski, U Oelfke.   

Abstract

The most recent experimental results obtained with laser-plasma accelerators are applied to radio-therapy simulations. The narrow electron beam, produced during the interaction of the laser with the gas jet, has a high charge (0.5 nC) and is quasimonoenergetic (170 +/- 20 MeV). The dose deposition is calculated in a water phantom placed at different distances from the diverging electron source. We show that, using magnetic fields to refocus the electron beam inside the water phantom, the transverse penumbra is improved. This electron beam is well suited for delivering a high dose peaked on the propagation axis, a sharp and narrow tranverse penumbra combined with a deep penetration.

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Year:  2006        PMID: 16485422     DOI: 10.1118/1.2140115

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  6 in total

Review 1.  Expanding the therapeutic index of radiation therapy by normal tissue protection.

Authors:  Pierre Montay-Gruel; Lydia Meziani; Chakradhar Yakkala; Marie-Catherine Vozenin
Journal:  Br J Radiol       Date:  2018-07-02       Impact factor: 3.039

2.  Comparison study of in vivo dose response to laser-driven versus conventional electron beam.

Authors:  Melanie Oppelt; Michael Baumann; Ralf Bergmann; Elke Beyreuther; Kerstin Brüchner; Josefin Hartmann; Leonhard Karsch; Mechthild Krause; Lydia Laschinsky; Elisabeth Leßmann; Maria Nicolai; Maria Reuter; Christian Richter; Alexander Sävert; Michael Schnell; Michael Schürer; Julia Woithe; Malte Kaluza; Jörg Pawelke
Journal:  Radiat Environ Biophys       Date:  2015-01-20       Impact factor: 1.925

3.  Ultra-high dose rate radiation production and delivery systems intended for FLASH.

Authors:  Jonathan Farr; Veljko Grilj; Victor Malka; Srinivasan Sudharsan; Marco Schippers
Journal:  Med Phys       Date:  2022-05-05       Impact factor: 4.506

4.  Focused very high-energy electron beams as a novel radiotherapy modality for producing high-dose volumetric elements.

Authors:  K Kokurewicz; E Brunetti; G H Welsh; S M Wiggins; M Boyd; A Sorensen; A J Chalmers; G Schettino; A Subiel; C DesRosiers; D A Jaroszynski
Journal:  Sci Rep       Date:  2019-07-25       Impact factor: 4.379

5.  A focused very high energy electron beam for fractionated stereotactic radiotherapy.

Authors:  Kristoffer Svendsen; Diego Guénot; Jonas Björklund Svensson; Kristoffer Petersson; Anders Persson; Olle Lundh
Journal:  Sci Rep       Date:  2021-03-12       Impact factor: 4.379

6.  Toward an effective use of laser-driven very high energy electrons for radiotherapy: Feasibility assessment of multi-field and intensity modulation irradiation schemes.

Authors:  Luca Labate; Daniele Palla; Daniele Panetta; Federico Avella; Federica Baffigi; Fernando Brandi; Fabio Di Martino; Lorenzo Fulgentini; Antonio Giulietti; Petra Köster; Davide Terzani; Paolo Tomassini; Claudio Traino; Leonida A Gizzi
Journal:  Sci Rep       Date:  2020-10-14       Impact factor: 4.379

  6 in total

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