Literature DB >> 16485412

Feasibility of delivering grid therapy using a multileaf collimator.

Jonathan K Ha1, Guowei Zhang, Shahid A Naqvi, William F Regine, Cedric X Yu.   

Abstract

The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mm x 10 mm and 5 mm x 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose (dmax), the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mm x 10 mm and 5 mm X 5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at dmax. The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.

Entities:  

Mesh:

Year:  2006        PMID: 16485412     DOI: 10.1118/1.2140116

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  16 in total

1.  Modelling responses to spatially fractionated radiation fields using preclinical image-guided radiotherapy.

Authors:  Karl Terence Butterworth; Mihaela Ghita; Stephen J McMahon; Conor K Mcgarry; Robert J Griffin; Alan R Hounsell; Kevin M Prise
Journal:  Br J Radiol       Date:  2016-09-15       Impact factor: 3.039

2.  Effective spatially fractionated GRID radiation treatment planning for a passive grid block.

Authors:  A Nobah; M Mohiuddin; S Devic; B Moftah
Journal:  Br J Radiol       Date:  2015-01       Impact factor: 3.039

3.  Feasibility Study of 3D-VMAT-Based GRID Therapy.

Authors:  Xin Zhang; Robert J Griffin; Edvaldo P Galhardo; Jose Penagaricano
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec

Review 4.  A Current Review of Spatial Fractionation: Back to the Future?

Authors:  Cole Billena; Atif J Khan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2019-01-23       Impact factor: 7.038

5.  Grid Block Design Based on Monte Carlo Simulated Dosimetry, the Linear Quadratic and Hug-Kellerer Radiobiological Models.

Authors:  Somayeh Gholami; Hassan Ali Nedaie; Francesco Longo; Mohammad Reza Ay; Sharifeh A Dini; Ali S Meigooni
Journal:  J Med Phys       Date:  2017 Oct-Dec

6.  Evaluation of a commercially-available block for spatially fractionated radiation therapy.

Authors:  Courtney Buckey; Sotirios Stathakis; Ken Cashon; Alonso Gutierrez; Carlos Esquivel; Chengyu Shi; Nikos Papanikolaou
Journal:  J Appl Clin Med Phys       Date:  2010-04-26       Impact factor: 2.102

Review 7.  Microbeam radiation therapy - grid therapy and beyond: a clinical perspective.

Authors:  Elisabeth Schültke; Jacques Balosso; Thomas Breslin; Guido Cavaletti; Valentin Djonov; Francois Esteve; Michael Grotzer; Guido Hildebrandt; Alexander Valdman; Jean Laissue
Journal:  Br J Radiol       Date:  2017-07-27       Impact factor: 3.039

8.  Spatially fractionated radiotherapy (GRID) using helical tomotherapy.

Authors:  Xin Zhang; Jose Penagaricano; Yulong Yan; Xiaoying Liang; Steven Morrill; Robert J Griffin; Peter Corry; Vaneerat Ratanatharathorn
Journal:  J Appl Clin Med Phys       Date:  2016-01-08       Impact factor: 2.102

9.  A novel external beam radiotherapy method for cervical cancer patients using virtual straight or bending boost areas; an in-silico feasibility study.

Authors:  Luca Cozzi; Sushil Beriwal; Esa Kuusela; Supriya Chopra; Hester Burger; Nanette Joubert; Antonella Fogliata; Jai Prakash Agarwal; Pat Kupelian
Journal:  Radiat Oncol       Date:  2021-06-14       Impact factor: 3.481

10.  Is grid therapy useful for all tumors and every grid block design?

Authors:  Somayeh Gholami; Hassan Ali Nedaie; Francesco Longo; Mohammad Reza Ay; Stacey Wright; Ali S Meigooni
Journal:  J Appl Clin Med Phys       Date:  2016-03-08       Impact factor: 2.102

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.