| Literature DB >> 16483924 |
Abstract
A mechanism that regulates K-Ras signaling specificity by altering its subcellular location is presented by Bivona et al. (2006). Phosphorylation of its membrane-anchoring domain by PKC drives K-Ras off of the plasma membrane and onto the outer mitochondrial membrane where it induces cell death.Entities:
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Year: 2006 PMID: 16483924 DOI: 10.1016/j.molcel.2006.02.002
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970