Literature DB >> 16482809

[Diagnosis and treatment of congenital infection caused by Trypanosoma cruzi in Brazil].

Alejandro O Luquetti1, João Carlos Pinto Dias, Aluizio Prata.   

Abstract

Diagnosis of congenital infection should be performed preferentially by the search of the parasite, through microhematocrit. Nevertheless, most of the infected mothers are living now in non-endemic areas, where the expertise for identification of the parasite is low. Furthermore, transmission near delivery or even at delivery do not allow that enough parasites will be detected when the baby is at the maternity. So, if parasites are not found or not searched, it is imperative that, in serologically confirmed mothers (two positive tests), the babies are recalled at six/eight months of age, to look for IgG antibodies. If they are present, the baby is infected and should be treated. Treatment in Brazil is with benznidazol, 10 mg/Kg/day, during 60 days. Certification of cure is obtained once a negative serology is obtained, as a rule after one year. A follow up each six months is suggested.

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Mesh:

Year:  2005        PMID: 16482809

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  6 in total

1.  Congenital Trypanosoma cruzi transmission in Santa Cruz, Bolivia.

Authors:  Caryn Bern; Manuela Verastegui; Robert H Gilman; Carlos Lafuente; Gerson Galdos-Cardenas; Maritza Calderon; Juan Pacori; Maria Del Carmen Abastoflor; Hugo Aparicio; Mark F Brady; Lisbeth Ferrufino; Noelia Angulo; Sarah Marcus; Charles Sterling; James H Maguire
Journal:  Clin Infect Dis       Date:  2009-12-01       Impact factor: 9.079

2.  The investigation of congenital infection by Trypanosoma cruzi in an endemic area of Chile: three protocols explored in a pilot project.

Authors:  I Zulantay; G Corral; M C Guzman; F Aldunate; W Guerra; I Cruz; A Araya; V Tapia; F Marquez; C Muñoz; W Apt
Journal:  Ann Trop Med Parasitol       Date:  2011-03

3.  Prevalence and risk factors for Chagas disease in pregnant women in Casanare, Colombia.

Authors:  Zulma M Cucunubá; Astrid C Flórez; Angela Cárdenas; Paula Pavía; Marleny Montilla; Rodrigo Aldana; Katherine Villamizar; Lyda C Ríos; Rubén S Nicholls; Concepción J Puerta
Journal:  Am J Trop Med Hyg       Date:  2012-10-01       Impact factor: 2.345

4.  Monitoring the parasite load in chronic Chagas disease patients: comparison between blood culture and quantitative real time PCR.

Authors:  Daniella Alchaar D'Ávila; Lúcia Maria C Galvão; Giovane R Sousa; Constança Britto; Otacilio C Moreira; Egler Chiari
Journal:  PLoS One       Date:  2018-11-29       Impact factor: 3.240

Review 5.  Diagnosis of animal trypanosomoses: proper use of current tools and future prospects.

Authors:  Marc Desquesnes; Alireza Sazmand; Marisa Gonzatti; Alain Boulangé; Géraldine Bossard; Sophie Thévenon; Geoffrey Gimonneau; Philippe Truc; Stéphane Herder; Sophie Ravel; Denis Sereno; Etienne Waleckx; Vincent Jamonneau; Philippe Jacquiet; Sathaporn Jittapalapong; David Berthier; Philippe Solano; Laurent Hébert
Journal:  Parasit Vectors       Date:  2022-06-27       Impact factor: 4.047

6.  Achievements and challenges upon the implementation of a program for national control of congenital Chagas in Bolivia: results 2004-2009.

Authors:  Cristina Alonso-Vega; Claire Billot; Faustino Torrico
Journal:  PLoS Negl Trop Dis       Date:  2013-07-11
  6 in total

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