Literature DB >> 16481691

Development of a simple control system for uniform proton dose distribution in a dual-ring double scattering method.

Teiji Nishio1, Shouji Kataoka, Masanori Tachibana, Kazutomo Matsumura, Naoya Uzawa, Hideki Saito, Toshinobu Sasano, Michiharu Yamaguchi, Takashi Ogino.   

Abstract

In proton radiotherapy with high focusing of irradiation on the tumour, it is important to obtain treatment beams with a highly uniform dose distribution. Uniform dose distribution in the clinical irradiation field can be obtained by the dual-ring double scattering method. This method is superior to the wobbler method, which uses electromagnetic deflection of the proton beams, because of the absence of the temporal structure of irradiation distribution. However, in the dual-ring double scattering method the condition of incident proton beams entering the scatter, especially the accuracy of the position of the incident proton beams with respect to the scatter, markedly affects the uniformity of the beam distribution in the irradiation field. In this study, to ensure the uniformity of dose distribution during treatment, we developed a control system equipped with an automatic fine adjustment of the beam axis and a mechanism for moving the second dual-ring scatter of the double scatters to the optimal position. Using this system, we achieved uniform dose distribution in the irradiation field during proton radiotherapy, with symmetry within +/-1% and flatness within 2%.

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Year:  2006        PMID: 16481691     DOI: 10.1088/0031-9155/51/5/014

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  5 in total

1.  Experimental verification of proton beam monitoring in a human body by use of activity image of positron-emitting nuclei generated by nuclear fragmentation reaction.

Authors:  Teiji Nishio; Aya Miyatake; Kazumasa Inoue; Tomoko Gomi-Miyagishi; Ryosuke Kohno; Satoru Kameoka; Keiichi Nakagawa; Takashi Ogino
Journal:  Radiol Phys Technol       Date:  2007-11-27

2.  In vivo proton dosimetry using a MOSFET detector in an anthropomorphic phantom with tissue inhomogeneity.

Authors:  Ryosuke Kohno; Kenji Hotta; Kana Matsubara; Shie Nishioka; Taeko Matsuura; Mitsuhiko Kawashima
Journal:  J Appl Clin Med Phys       Date:  2012-03-08       Impact factor: 2.102

3.  Evaluation of monitor unit calculation based on measurement and calculation with a simplified Monte Carlo method for passive beam delivery system in proton beam therapy.

Authors:  Kenji Hotta; Ryosuke Kohno; Kohsuke Nagafuchi; Hidenori Yamaguchi; Ryohei Tansho; Yoshihisa Takada; Tetsuo Akimoto
Journal:  J Appl Clin Med Phys       Date:  2015-09-08       Impact factor: 2.102

4.  Proton dose distribution measurements using a MOSFET detector with a simple dose-weighted correction method for LET effects.

Authors:  Ryosuke Kohno; Kenji Hotta; Taeko Matsuura; Kana Matsubara; Shie Nishioka; Teiji Nishio; Mitsuhiko Kawashima; Takashi Ogino
Journal:  J Appl Clin Med Phys       Date:  2011-04-04       Impact factor: 2.102

5.  Enhanced radiobiological effects at the distal end of a clinical proton beam: in vitro study.

Authors:  Yoshitaka Matsumoto; Taeko Matsuura; Mami Wada; Yusuke Egashira; Teiji Nishio; Yoshiya Furusawa
Journal:  J Radiat Res       Date:  2014-05-13       Impact factor: 2.724

  5 in total

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