A new hypothesis for electrical transmission in the mammalian central nervous system.

It has been previously shown that the anatomical synapse does not exist in the living central nervous system, and that receptors are unlikely to be unique molecules sited on particular locations in or on the cell membrane. These conclusions and the rapidity of action of intravenously administered substances necessitated the adumbration of a new electrical hypothesis for the mechanism whereby signals pass from one part of the brain and spinal cord to another. The hypothesis proposed implies some testable predictions.