| Literature DB >> 16481469 |
Abstract
Multiple members of the casein kinase I family of serine/threonine protein kinases are involved in positive and negative roles in Wnt and Hedgehog signaling. Here I review these roles, including recent results on casein kinase I (CKI) phosphorylation and activation of LRP6, and CKI phosphorylation of Ci and mediation of Ci-Slimb/beta-TrCP binding.Entities:
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Year: 2006 PMID: 16481469 DOI: 10.1101/gad.1394306
Source DB: PubMed Journal: Genes Dev ISSN: 0890-9369 Impact factor: 11.361