Literature DB >> 16481210

Roles of activin in tissue repair, fibrosis, and inflammatory disease.

Sabine Werner1, Christian Alzheimer.   

Abstract

Activins are transforming growth factor beta superfamily members, which were originally identified as inducers of follicle-stimulating hormone release from the pituitary. In recent years, however, additional functions of activins have been discovered, including a role in the morphogenesis of various tissues and organs. In addition, they have been identified as novel players in inflammation and repair, and are most likely involved in the pathogenesis of inflammatory and fibrotic human diseases. In this review we highlight recent data regarding the expression and function of activins in tissue repair, fibrosis, and inflammation.

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Year:  2006        PMID： 16481210     DOI： 10.1016/j.cytogfr.2006.01.001

Source DB:  PubMed          Journal:  Cytokine Growth Factor Rev        ISSN： 1359-6101            Impact factor:   7.638


  78 in total

1.  Comparison of the effects of recombinant human bone morphogenetic protein-2 and -9 on bone formation in rat calvarial critical-size defects.

Authors:  Toshiaki Nakamura; Yoshinori Shirakata; Yukiya Shinohara; Richard J Miron; Kozue Hasegawa-Nakamura; Masako Fujioka-Kobayashi; Kazuyuki Noguchi
Journal:  Clin Oral Investig       Date:  2017-02-14       Impact factor: 3.573

2.  Activin A-mediated epithelial de-differentiation contributes to injury repair in an in vitro gastrointestinal reflux model.

Authors:  Cedric Roudebush; Alma Catala-Valentin; Thomas Andl; Gregoire F Le Bras; Claudia D Andl
Journal:  Cytokine       Date:  2019-07-29       Impact factor: 3.861

3.  Nasal Spray to the Rescue of Neurons in Stroke.

Authors:  Christian Alzheimer
Journal:  Mol Ther       Date:  2018-09-11       Impact factor: 11.454

4.  Serum follistatin in patients with prostate cancer metastatic to the bone.

Authors:  Francesca Maria Tumminello; Giuseppe Badalamenti; Fabio Fulfaro; Lorena Incorvaia; Marilena Crescimanno; Carla Flandina; Maria Vittoria Sepporta; Gaetano Leto
Journal:  Clin Exp Metastasis       Date:  2010-07-11       Impact factor: 5.150

5.  Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair.

Authors:  Maria Antsiferova; Jennifer E Klatte; Enikö Bodó; Ralf Paus; José L Jorcano; Martin M Matzuk; Sabine Werner; Heidi Kögel
Journal:  Lab Invest       Date:  2008-12-15       Impact factor: 5.662

6.  Activin A is stimulated by tumor necrosis factor-alpha and modulates collagen gene expression in human amniotic cells.

Authors:  Y Abe; M Komatsubara; M Saito; M Toda; H Shinozaki; T Tamura; Y Kasahara; H Sedakata; T Minegishi
Journal:  J Endocrinol Invest       Date:  2013-02-04       Impact factor: 4.256

Review 7.  Activins and activin antagonists in hepatocellular carcinoma.

Authors:  Alev Deli; Emanuel Kreidl; Stefan Santifaller; Barbara Trotter; Katja Seir; Walter Berger; Rolf Schulte-Hermann; Chantal Rodgarkia-Dara; Michael Grusch
Journal:  World J Gastroenterol       Date:  2008-03-21       Impact factor: 5.742

8.  Role of activins and inducible nitric oxide in the pathogenesis of ectopic pregnancy in patients with or without Chlamydia trachomatis infection.

Authors:  Bassem Refaat; Majedah Al-Azemi; Ian Geary; Adrian Eley; William Ledger
Journal:  Clin Vaccine Immunol       Date:  2009-08-19

9.  Peroxisome proliferator-activated receptor gamma down-regulates follistatin in intestinal epithelial cells through SP1.

Authors:  Brian M Necela; Weidong Su; E Aubrey Thompson
Journal:  J Biol Chem       Date:  2008-09-03       Impact factor: 5.157

10.  Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

Authors:  Maria Semitekolou; Themis Alissafi; Maria Aggelakopoulou; Evangelia Kourepini; Harsha H Kariyawasam; Antony B Kay; Douglas S Robinson; Clare M Lloyd; Vily Panoutsakopoulou; Georgina Xanthou
Journal:  J Exp Med       Date:  2009-07-20       Impact factor: 14.307
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