Literature DB >> 16480437

An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit.

L Anderson1, I Quasim, R Soutar, M Steven, A Macfie, W Korte.   

Abstract

Cardiac surgery is estimated to use 20% of the UK blood supply. However, there has been much interest recently in decreasing red cell and blood product use not only to ease strain on blood stocks or avoid potential transmission of infection but also to decrease post-operative transfusion-related complications. Coagulopathies are not uncommon in cardiac surgical patients, but the time lapse for reporting conventional laboratory results has been highlighted as an obstacle to the appropriate use of blood products. Accordingly, much interest has arisen in rapid near-patient testing of coagulation and, in January 2002, a thromboelastometer (ROTEM, Pentapharm, Germany) was purchased for our unit. This audit sought to assess its impact by retrospective analysis of 990 sequential patients' demographic data and transfusion details covering 6 months prior to its introduction and 6 months after. In the 6 months prior to its introduction, red cells were used in 60% of patients and fresh frozen plasma (FFP) and platelets used in 17 and 16% of patients, respectively. In the following 6 months, red cell use had fallen to 53% and FFP and platelets to 12 and 11%, respectively (P < 0.05). Introduction of thromboelastometry has significantly decreased our use of red cells and blood products.

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Year:  2006        PMID: 16480437     DOI: 10.1111/j.1365-3148.2006.00645.x

Source DB:  PubMed          Journal:  Transfus Med        ISSN: 0958-7578            Impact factor:   2.019


  29 in total

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Authors:  Natalie P Kreitzer; Jordan Bonomo; Daniel Kanter; Christopher Zammit
Journal:  Neurocrit Care       Date:  2015-12       Impact factor: 3.210

2.  [Bedside thrombelastography].

Authors:  C von Heymann; C Rosenthal; T Volk; C Spies
Journal:  Anaesthesist       Date:  2007-12       Impact factor: 1.041

Review 3.  [Management of hemostasis disorders after extracorporeal circulation. A clinical therapy algorithm].

Authors:  C Jámbor; D Bremerich; A Moritz; E Seifried; B Zwissler
Journal:  Anaesthesist       Date:  2008-04       Impact factor: 1.041

4.  TEG-Directed Transfusion in Complex Cardiac Surgery: Impact on Blood Product Usage.

Authors:  Kevin Fleming; Roberta E Redfern; Rebekah L March; Nathan Bobulski; Michael Kuehne; John T Chen; Michael Moront
Journal:  J Extra Corpor Technol       Date:  2017-12

5.  Concerning Hänecke P, Klouche M: Thrombelastography Today: Practicability and Analytical Power. Transfus Med Hemother 2007;34:421-428.

Authors:  Thomas Ebinger
Journal:  Transfus Med Hemother       Date:  2008-07-21       Impact factor: 3.747

6.  Alternative procedures for reducing allogeneic blood transfusion in elective orthopedic surgery.

Authors:  Kathrin Kleinert; Oliver M Theusinger; Johannes Nuernberg; Clément M L Werner
Journal:  HSS J       Date:  2010-01-28

7.  Impact of experimental haemodilution on platelet function, thrombin generation and clot firmness: effects of different coagulation factor concentrates.

Authors:  Carolina Caballo; Gines Escolar; Maribel Diaz-Ricart; Irene Lopez-Vílchez; Miguel Lozano; Joan Cid; Marcos Pino; Joan Beltrán; Misericordia Basora; Arturo Pereira; Ana M Galan
Journal:  Blood Transfus       Date:  2012-09-19       Impact factor: 3.443

8.  Redistribution and hemostatic action of recombinant activated factor VII associated with platelets.

Authors:  Irene Lopez-Vilchez; Ulla Hedner; Carmen Altisent; Maribel Diaz-Ricart; Gines Escolar; Ana M Galan
Journal:  Am J Pathol       Date:  2011-06       Impact factor: 4.307

9.  Adaptive force sonorheometry for assessment of whole blood coagulation.

Authors:  F William Mauldin; Francesco Viola; Theresa C Hamer; Eman M Ahmed; Shawna B Crawford; Doris M Haverstick; Michael B Lawrence; William F Walker
Journal:  Clin Chim Acta       Date:  2010-01-22       Impact factor: 3.786

Review 10.  Thrombelastography and tromboelastometry in assessing coagulopathy in trauma.

Authors:  Pär I Johansson; Trine Stissing; Louise Bochsen; Sisse R Ostrowski
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2009-09-23       Impact factor: 2.953

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