Literature DB >> 16480399

Despite high satisfaction, majority of gastro-oesophageal reflux disease patients continue to use proton pump inhibitors after antireflux surgery.

A Madan1, A Minocha.   

Abstract

BACKGROUND: While antireflux surgery is effective in controlling symptoms of gastro-oesophageal reflux, its role in eliminating the use of antireflux medicines after surgery and as such its long-term cost-effectiveness remains controversial. AIM: To assess the patient satisfaction and the continued medication use following laparoscopic Nissen fundoplication at a tertiary level community hospital.
METHODS: Adult patients who underwent laparoscopic Nissen fundoplication at our institution over a period of over 3 years were asked to complete a questionnaire recording their demographic information, date and reason for the surgery, preprocedure and postprocedure symptoms, smoking and alcohol use, and medication use preoperatively and post-operatively. Patients were also asked about their satisfaction with surgery.
RESULTS: One hundred patients participated in the study. Overall, 90% patients experienced satisfaction with their surgery. Eighty percentage patients were willing to undergo surgery again, if needed. Over two-thirds (67%) patients had decrease in the severity of their symptoms. None of the patients had worsening of symptoms post-operatively. However, 80% patients were still taking antireflux medications including proton pump inhibitors (53%).
CONCLUSIONS: Most patients continue to use antireflux medications including after laparoscopic Nissen fundoplication despite high satisfaction with surgery.

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Year:  2006        PMID: 16480399     DOI: 10.1111/j.1365-2036.2006.02788.x

Source DB:  PubMed          Journal:  Aliment Pharmacol Ther        ISSN: 0269-2813            Impact factor:   8.171


  8 in total

1.  Weighing the option of surgical therapy in the treatment of gastroesophageal reflux.

Authors:  Carlos A Pellegrini
Journal:  Gastroenterol Hepatol (N Y)       Date:  2008-04

Review 2.  Cost-effectiveness of proton pump inhibitors versus laparoscopic Nissen fundoplication for patients with gastroesophageal reflux disease: a systematic review of the literature.

Authors:  Anthony S Thijssen; Ivo A M J Broeders; G Ardine de Wit; Werner A Draaisma
Journal:  Surg Endosc       Date:  2011-04-13       Impact factor: 4.584

3.  Gastrointestinal symptoms and patient satisfaction more than 1 year after laparoscopic Nissen fundoplication.

Authors:  Daniel McKenna; Gretchen Beverstein; Jon Gould
Journal:  Surg Endosc       Date:  2010-12-07       Impact factor: 4.584

4.  Laparoscopic fundoplication takedown with conversion to Roux-en-Y gastric bypass leads to excellent reflux control and quality of life after fundoplication failure.

Authors:  Dimitrios Stefanidis; Fernando Navarro; Vedra A Augenstein; Keith S Gersin; B Todd Heniford
Journal:  Surg Endosc       Date:  2012-06-13       Impact factor: 4.584

5.  Surgical management of gastroesophageal reflux disease in obesity.

Authors:  Sayeed Ikramuddin
Journal:  Dig Dis Sci       Date:  2008-07-29       Impact factor: 3.199

6.  Medical or surgical management of GERD patients with Barrett's esophagus: the LOTUS trial 3-year experience.

Authors:  S E Attwood; L Lundell; J G Hatlebakk; S Eklund; O Junghard; J-P Galmiche; C Ell; R Fiocca; T Lind
Journal:  J Gastrointest Surg       Date:  2008-08-16       Impact factor: 3.452

7.  Evaluation of clinical outcome after laparoscopic antireflux surgery in clinical practice: still a controversial issue.

Authors:  Sandro Contini; Carmelo Scarpignato
Journal:  Minim Invasive Surg       Date:  2011-09-11

8.  Recurrent heartburn after laparoscopic fundoplication is not always recurrent reflux.

Authors:  Sarah K Thompson; Glyn G Jamieson; Jennifer C Myers; Kin-Fah Chin; David I Watson; Peter G Devitt
Journal:  J Gastrointest Surg       Date:  2007-05       Impact factor: 3.267

  8 in total

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