Literature DB >> 1648035

Synthesis and characterization of [186Re]rhenium(V)dimercaptosuccinic acid: a possible tumour radiotherapy agent.

M M Bisunadan1, P J Blower, S E Clarke, J Singh, M J Went.   

Abstract

[186Re]Re(V)DMSA, a beta-emitting analogue of the tumour imaging radiopharmaceutical pentavalent [99mTc]Tc(V)DMSA of possible value in tumour therapy, is readily prepared by stannous reduction of [186Re]ReO4 in the presence of dimercaptosuccinic acid at 100 degrees C using a commercial DMSA kit as used for renal imaging with 99mTc, and purified using a disposable sample preparation column. The complex has been identified as [ReO(DMSA)2] by NMR, optical and i.r., spectroscopy and elemental analysis.

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Year:  1991        PMID: 1648035     DOI: 10.1016/0883-2889(91)90068-c

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum A        ISSN: 0883-2889


  2 in total

1.  In vitro and in vivo studies with pentavalent technetium-99m dimercaptosuccinic acid.

Authors:  A S Lam; M R Puncher; P J Blower
Journal:  Eur J Nucl Med       Date:  1996-12

2.  Opportunities and challenges for metal chemistry in molecular imaging: from gamma camera imaging to PET and multimodality imaging.

Authors:  Richard Southworth; Rafael Torres Martin de Rosales; Levente K Meszaros; Michelle T Ma; Gregory E D Mullen; Gilbert Fruhwirth; Jennifer D Young; Cinzia Imberti; Julia Bagunya-Torres; Erica Andreozzi; Philip J Blower
Journal:  Adv Inorg Chem       Date:  2015-11-16       Impact factor: 3.282

  2 in total

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