Literature DB >> 16480307

Random sampling-high dimensional model representation (RS-HDMR) and orthogonality of its different order component functions.

Genyuan Li1, Jishan Hu, Sheng-Wei Wang, Panos G Georgopoulos, Jacqueline Schoendorf, Herschel Rabitz.   

Abstract

High dimensional model representation is under active development as a set of quantitative model assessment and analysis tools for capturing high-dimensional input-output system behavior based on a hierarchy of functions of increasing dimensions. The HDMR component functions are optimally constructed from zeroth order to higher orders step-by-step. This paper extends the definitions of HDMR component functions to systems whose input variables may not be independent. The orthogonality of the higher order terms with respect to the lower order ones guarantees the best improvement in accuracy for the higher order approximations. Therefore, the HDMR component functions are constructed to be mutually orthogonal. The RS-HDMR component functions are efficiently constructed from randomly sampled input-output data. The previous introduction of polynomial approximations for the component functions violates the strictly desirable orthogonality properties. In this paper, new orthonormal polynomial approximation formulas for the RS-HDMR component functions are presented that preserve the orthogonality property. An integrated exposure and dose model as well as ionospheric electron density determined from measured ionosonde data are used as test cases, which show that the new method has better accuracy than the prior one.

Mesh:

Substances:

Year:  2006        PMID: 16480307     DOI: 10.1021/jp054148m

Source DB:  PubMed          Journal:  J Phys Chem A        ISSN: 1089-5639            Impact factor:   2.781


  7 in total

1.  Estimation of Sobol's Sensitivity Indices under Generalized Linear Models.

Authors:  Rong Lu; Danxin Wang; Min Wang; Grzegorz A Rempala
Journal:  Commun Stat Theory Methods       Date:  2017-11-20       Impact factor: 0.893

2.  Dissecting enzyme regulation by multiple allosteric effectors: nucleotide regulation of aspartate transcarbamoylase.

Authors:  Joshua D Rabinowitz; Jennifer J Hsiao; Kimberly R Gryncel; Evan R Kantrowitz; Xiao-Jiang Feng; Genyuan Li; Herschel Rabitz
Journal:  Biochemistry       Date:  2008-05-03       Impact factor: 3.162

3.  A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems.

Authors:  Hong-Xuan Zhang; John Goutsias
Journal:  BMC Bioinformatics       Date:  2010-05-12       Impact factor: 3.169

4.  Identifying biological network structure, predicting network behavior, and classifying network state with High Dimensional Model Representation (HDMR).

Authors:  Miles A Miller; Xiao-Jiang Feng; Genyuan Li; Herschel A Rabitz
Journal:  PLoS One       Date:  2012-06-18       Impact factor: 3.240

5.  Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation.

Authors:  Philip M Jedrzejewski; Ioscani Jimenez del Val; Antony Constantinou; Anne Dell; Stuart M Haslam; Karen M Polizzi; Cleo Kontoravdi
Journal:  Int J Mol Sci       Date:  2014-03-14       Impact factor: 5.923

6.  RACIPE: a computational tool for modeling gene regulatory circuits using randomization.

Authors:  Bin Huang; Dongya Jia; Jingchen Feng; Herbert Levine; José N Onuchic; Mingyang Lu
Journal:  BMC Syst Biol       Date:  2018-06-19

7.  High dimensional model representation of log likelihood ratio: binary classification with SNP data.

Authors:  Ali Foroughi Pour; Maciej Pietrzak; Lara E Sucheston-Campbell; Ezgi Karaesmen; Lori A Dalton; Grzegorz A Rempała
Journal:  BMC Med Genomics       Date:  2020-09-21       Impact factor: 3.063

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.