| Literature DB >> 16480210 |
Hamid Dehghani1, Scott C Davis, Shudong Jiang, Brian W Pogue, Keith D Paulsen, Michael S Patterson.
Abstract
Spectrally resolved bioluminescence optical tomography is an approach to recover images of luciferase activity within a volume using multiwavelength emission data from internal bioluminescence sources. The underlying problem of uniqueness associated with nonspectrally resolved intensity-based bioluminescence tomography is highlighted. Reconstructed images of bioluminescence are presented by using as input both simulated and real multiwavelength data from a tissue-simulating phantom. The location of the internal bioluminescence is obtained with 1 mm accuracy. Further, the amplitude of the reconstructed source is proportional to the actual bioluminescence intensity.Mesh:
Substances:
Year: 2006 PMID: 16480210 DOI: 10.1364/ol.31.000365
Source DB: PubMed Journal: Opt Lett ISSN: 0146-9592 Impact factor: 3.776