Literature DB >> 1647975

Activation of Epstein-Barr virus promoters by a growth-factor and a glucocorticoid.

C Schuster1, S Chasserot-Golaz, G Beck.   

Abstract

Transforming growth factor-beta (TGF-beta) and a glucocorticosteroid, Dexamethasone (DXM), both cause transcriptional induction of Epstein-Barr virus (EBV) early antigens (EA) in Daudi lymphoma cells. The viral induction occurs through the viral promoter DR overlapping an origin of replication which is active during the lytic cycle. Each hormone requires specific regions on the DR promoter. Since these regions also mediate the action of two viral transcription factors, EB1 and R, it may be emphasized that EB1 and/or R are involved in the EA induction process by TGF-beta and by DXM.

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Year:  1991        PMID： 1647975     DOI： 10.1016/0014-5793(91)80767-w

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  6 in total

1.  MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation.

Authors:  Qinyan Yin; Xia Wang; Claire Fewell; Jennifer Cameron; Hanqing Zhu; Melody Baddoo; Zhen Lin; Erik K Flemington
Journal:  J Virol       Date:  2010-04-28       Impact factor: 5.103

2.  Induction of lytic Epstein-Barr virus (EBV) infection by synergistic action of rituximab and dexamethasone renders EBV-positive lymphoma cells more susceptible to ganciclovir cytotoxicity in vitro and in vivo.

Authors:  Masanori Daibata; Kentaro Bandobashi; Masayuki Kuroda; Shosuke Imai; Isao Miyoshi; Hirokuni Taguchi
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

3.  Differential effects of nerve growth factor and dexamethasone on herpes simplex virus type 1 oriL- and oriS-dependent DNA replication in PC12 cells.

Authors:  M A Hardwicke; P A Schaffer
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

4.  The lytic transition of Epstein-Barr virus is imitated by recombinant B-cells.

Authors:  M Marschall; P Alliger; F Schwarzmann; C Bogedain; M Brand; B Reichelt; G Glaser; H Wolf
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

5.  Predictors of delayed-type hypersensitivity to Candida albicans and anti-Epstein-Barr virus antibody among children in Kilimanjaro, Tanzania.

Authors:  Katherine Wander; Bettina Shell-Duncan; Eleanor Brindle; Kathleen O'Connor
Journal:  Am J Phys Anthropol       Date:  2013-03-04       Impact factor: 2.868

6.  Epstein-Barr virus reactivation after superinfection of the BJAB-B1 and P3HR-1 cell lines with cytomegalovirus.

Authors:  Rodney Arcenas; Raymond H Widen
Journal:  BMC Microbiol       Date:  2002-07-23       Impact factor: 3.605
  6 in total

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