Literature DB >> 16478692

MRI-guided immunotherapy development for multiple sclerosis in a primate.

Bert A 't Hart1, Paul Smith, Sandra Amor, Gustav J Strijkers, Erwin L A Blezer.   

Abstract

Multiple sclerosis is a serious neurological disease that affects 1 in 1000 young adults in Europe and the USA. The development of an effective therapy for this enigmatic disease is plagued by the failure of many treatments to reproduce in patients the promising effects observed in animal models. This review describes a new preclinical model in a non-human primate that might help to bridge the gap between currently used animal models and the patients.

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Year:  2006        PMID： 16478692     DOI： 10.1016/S1359-6446(05)03673-1

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  11 in total

1.  The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease.

Authors:  Bert A 't Hart; David H Abbott; Katsuki Nakamura; Eberhard Fuchs
Journal:  Drug Discov Today       Date:  2012-06-21       Impact factor: 7.851

Review 2.  Anatomical and functional neuroimaging in awake, behaving marmosets.

Authors:  Afonso C Silva
Journal:  Dev Neurobiol       Date:  2016-10-21       Impact factor: 3.964

Review 3.  Experimental autoimmune encephalomyelitis in the common marmoset, a bridge between rodent EAE and multiple sclerosis for immunotherapy development.

Authors:  Yolanda S Kap; Jon D Laman; Bert A 't Hart
Journal:  J Neuroimmune Pharmacol       Date:  2009-10-14       Impact factor: 4.147

4.  An embedded four-channel receive-only RF coil array for fMRI experiments of the somatosensory pathway in conscious awake marmosets.

Authors:  Daniel Papoti; Cecil Chern-Chyi Yen; Julie B Mackel; Hellmut Merkle; Afonso C Silva
Journal:  NMR Biomed       Date:  2013-05-22       Impact factor: 4.044

Review 5.  Experimental autoimmune encephalomyelitis in the common marmoset: a translationally relevant model for the cause and course of multiple sclerosis.

Authors:  Bert A 't Hart
Journal:  Primate Biol       Date:  2019-05-10

6.  Collagen-induced arthritis in common marmosets: a new nonhuman primate model for chronic arthritis.

Authors:  Michel P M Vierboom; Elia Breedveld; Ivanela Kondova; Bert A 't Hart
Journal:  Arthritis Res Ther       Date:  2010-10-26       Impact factor: 5.156

7.  Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis.

Authors:  S Anwar Jagessar; Bruno Gran; Nicole Heijmans; Jan Bauer; Jon D Laman; Bert A 't Hart; Cris S Constantinescu
Journal:  J Neuroimmune Pharmacol       Date:  2011-10-20       Impact factor: 4.147

Review 8.  Overview of models, methods, and reagents developed for translational autoimmunity research in the common marmoset (Callithrix jacchus).

Authors:  S Anwar Jagessar; Michel Vierboom; Erwin L A Blezer; Jan Bauer; Bert A 't Hart; Yolanda S Kap
Journal:  Exp Anim       Date:  2013

9.  Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters.

Authors:  Jaeho Jang; Song Lee; Hyun Jeong Oh; Yoori Choi; Jae Hyouk Choi; Do Won Hwang; Dong Soo Lee
Journal:  EJNMMI Res       Date:  2016-04-26       Impact factor: 3.138

Review 10.  Multiple sclerosis and drug discovery: A work of translation.

Authors:  Bert A 't Hart; Antonio Luchicchi; Geert J Schenk; Joep Killestein; Jeroen J G Geurts
Journal:  EBioMedicine       Date:  2021-05-24       Impact factor: 8.143
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