| Literature DB >> 16478176 |
Anders Hamberg1, Stina Lundgren, Maël Penhoat, Christina Moberg, Karl Hult.
Abstract
The reaction yield and enantiomeric excess of O-acetylated cyanohydrin reaction products from a library of chiral catalysts can be analyzed by a three-step screening method. Alcohol dehydrogenase and NADH are used to analyze unreacted substrate. A lipase with absolute specificity converts one enantiomer to a quantifiable product before the remaining enantiomer is hydrolyzed with an unspecific esterase and quantified.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16478176 DOI： 10.1021/ja058474r
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419