Literature DB >> 1647766

Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid.

J Yatsunami1, H Fujiki, M Suganuma, S Yoshizawa, J E Eriksson, M O Olson, R D Goldman.   

Abstract

Okadaic acid and dinophysistoxin-1 (35-methylokadaic acid) induced hyperphosphorylation of a 58 kDa protein in primary human fibroblasts, due to inhibition of protein phosphatase 1 and 2A activities. The protein was present in the nuclear and cytosolic fractions. Its pI was 5.3. The hyperphosphorylated protein reacted with monoclonal and polyclonal anti-vimentin antibodies, but not with anti-nucleolin antibody. Phosphorylation of vimentin was stimulated in vitro by dinophysistoxin-1 dose-dependently in the presence of protein phosphatase 2A and protein kinases.

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Year:  1991        PMID： 1647766     DOI： 10.1016/0006-291x(91)90662-q

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Cytoskeletal integrity in interphase cells requires protein phosphatase activity.

Authors:  J E Eriksson; D L Brautigan; R Vallee; J Olmsted; H Fujiki; R D Goldman
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

2.  Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55.

Authors:  P Turowski; T Myles; B A Hemmings; A Fernandez; N J Lamb
Journal:  Mol Biol Cell       Date:  1999-06       Impact factor: 4.138

3.  Suppression by carotenoids of microcystin-induced morphological changes in mouse hepatocytes.

Authors:  R Matsushima-Nishiwaki; Y Shidoji; S Nishiwaki; T Yamada; H Moriwaki; Y Muto
Journal:  Lipids       Date:  1995-11       Impact factor: 1.880

4.  Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17β-estradiol treatment.

Authors:  Rahul Upadhyay; Ryan D'Souza; Shobha Sonawane; Reshma Gaonkar; Shilpa Pathak; Aditi Jhadav; N H Balasinor
Journal:  Histochem Cell Biol       Date:  2011-09-14       Impact factor: 4.304

Review 5.  Inroads into the structure and function of intermediate filament networks.

Authors:  Robert D Goldman; Megan M Cleland; S N Prasanna Murthy; Saleemulla Mahammad; Edward R Kuczmarski
Journal:  J Struct Biol       Date:  2011-11-18       Impact factor: 2.867

6.  Autophagosome-lysosome fusion is facilitated by plectin-stabilized actin and keratin 8 during macroautophagic process.

Authors:  Sumin Son; Ahruem Baek; Jong Hun Lee; Dong-Eun Kim
Journal:  Cell Mol Life Sci       Date:  2022-01-26       Impact factor: 9.261

7.  Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition.

Authors:  Feng Yang; Navdeep Jaitly; Hemalatha Jayachandran; Quanzhou Luo; Matthew E Monroe; Xiuxia Du; Marina A Gritsenko; Rui Zhang; David J Anderson; Samuel O Purvine; Joshua N Adkins; Ronald J Moore; Heather M Mottaz; Shi-Jian Ding; Mary S Lipton; David G Camp; Harold R Udseth; Richard D Smith; Sandra Rossie
Journal:  J Proteome Res       Date:  2007-10-12       Impact factor: 4.466

8.  Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors.

Authors:  I Holen; P B Gordon; P E Strømhaug; T O Berg; M Fengsrud; A Brech; N Roos; T Berg; P O Seglen
Journal:  Biochem J       Date:  1995-10-01       Impact factor: 3.857

9.  Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization.

Authors:  Vanessa Valdiglesias; Juan Fernández-Tajes; Eduardo Pásaro; Josefina Méndez; Blanca Laffon
Journal:  BMC Genomics       Date:  2012-01-27       Impact factor: 3.969

10.  Identification of dynamic changes in proteins associated with the cellular cytoskeleton after exposure to okadaic acid.

Authors:  Jill A Opsahl; Sonja Ljostveit; Therese Solstad; Kristin Risa; Peter Roepstorff; Kari E Fladmark
Journal:  Mar Drugs       Date:  2013-05-24       Impact factor: 5.118
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