| Literature DB >> 16477468 |
R Aschoff1, A Baldauf, S Leike, M P Wirth, M Meurer.
Abstract
Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men. The cause is a polymicrobial infection associated with superficial trauma, urological diseases and operations, as well as colorectal diseases. Diabetes mellitus, alcoholism, immunosuppression and other severe illnesses are frequent co-factors. Immediate administration of systemic broad-spectrum antibiotic therapy with coverage of both gram-positive and gram-negative bacteria combined with surgical debridement and intensive medical care can lower the high mortality rate of this condition.Entities:
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Year: 2006 PMID: 16477468 DOI: 10.1007/s00105-006-1101-3
Source DB: PubMed Journal: Hautarzt ISSN: 0017-8470 Impact factor: 0.751