Literature DB >> 16475977

Disruption of metabolic pathways--perspectives for the treatment of cancer.

Eliana P Araujo1, José Barreto Carvalheira, Licio A Velloso.   

Abstract

Several growth-promoting signaling pathways have tight molecular connections with metabolic-related signal transduction systems. By controlling these pathways, cancer cells gain autonomy over energy-acquiring systems and, thus, expand their potential for proliferation. Here, we discuss the use of drug and antisense oligonucleotide approaches to inhibit metabolic pathways in cancer cells and their potential use in the therapeutics of cancer.

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Year:  2006        PMID： 16475977     DOI： 10.2174/156800906775471734

Source DB:  PubMed          Journal:  Curr Cancer Drug Targets        ISSN： 1568-0096            Impact factor:   3.428


  7 in total

1.  Identification of multiple metabolic enzymes from mice cochleae tissue using a novel functional proteomics technology.

Authors:  David L Wang; Hui Li; Ruqiang Liang; Jianxin Bao
Journal:  PLoS One       Date:  2015-03-26       Impact factor: 3.240

2.  Bead Based Proteome Enrichment Enhances Features of the Protein Elution Plate (PEP) for Functional Proteomic Profiling.

Authors:  Xing Wang; Michael Davies; Swapan Roy; Matthew Kuruc
Journal:  Proteomes       Date:  2015-12-08

3.  Identification of potential serum biomarkers for breast cancer using a functional proteomics technology.

Authors:  David L Wang; Chuanguang Xiao; Guofeng Fu; Xing Wang; Liang Li
Journal:  Biomark Res       Date:  2017-03-14

4.  Identification of metabolites with anticancer properties by computational metabolomics.

Authors:  Adrian K Arakaki; Roman Mezencev; Nathan J Bowen; Ying Huang; John F McDonald; Jeffrey Skolnick
Journal:  Mol Cancer       Date:  2008-06-17       Impact factor: 27.401

5.  Identification of functional metabolic biomarkers from lung cancer patient serum using PEP technology.

Authors:  Zhenyu Sun; Xiaofeng Chen; Gan Wang; Liang Li; Guofeng Fu; Matthew Kuruc; Xing Wang
Journal:  Biomark Res       Date:  2016-06-01

Review 6.  Role of Mitochondria-Cytoskeleton Interactions in the Regulation of Mitochondrial Structure and Function in Cancer Stem Cells.

Authors:  Jungmin Kim; Jae-Ho Cheong
Journal:  Cells       Date:  2020-07-14       Impact factor: 6.600

7.  Dual Mechanisms of Metabolism and Gene Expression of the CCRF-CEM Leukemia Cells under Glucocorticoid Treatment.

Authors:  George I Lambrou; Theodoros Karakonstantakis; Spiros Vlahopoulos; Apostolos Zaravinos
Journal:  Int J Mol Sci       Date:  2021-05-31       Impact factor: 5.923
  7 in total

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