| Literature DB >> 1647574 |
P J Provost1, D L Krah, B J Kuter, D H Morton, T L Schofield, E H Wasmuth, C J White, W J Miller, R W Ellis.
Abstract
An enzyme-linked immunosorbent assay for antibodies to varicella-zoster virus (VZV), using purified viral glycoproteins as antigen (gpELISA), was compared with other assays for measuring vaccine-induced antibody responses. The gpELISA was more sensitive than conventional assays, proved highly specific for VZV and agreed well with an assay for neutralizing antibody activity. It was successfully applied to large-scale testing of live varicella vaccine in humans.Entities:
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Year: 1991 PMID: 1647574 DOI: 10.1016/0264-410x(91)90266-9
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641