Literature DB >> 16474519

Diagnosis and management of patients with overactive bladder syndrome and abnormal detrusor activity.

Michelle Jo Semins1, Michael B Chancellor.   

Abstract

Overactive bladder syndrome (OABS) is a widely recognized syndrome with symptoms that can include urinary urgency, frequency, nocturia, and incontinence. Although there may be several causative factors for OABS, detrusor overactivity is the most common. In addition, urinary incontinence can also be due to a distinct but equally bothersome condition underactive bladder syndrome, or detrusor underactivity. The incomplete bladder emptying that characterizes detrusor underactivity often arises from impaired contractile function of the detrusor muscle. The variations in etiologies of the two syndromes necessitate patient evaluations tailored to individual symptom presentation. Increased awareness of the differences between the manifestations of OABS and underactive bladder syndrome call for specific approaches to the management of bladder dysfunction.

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Year:  2004        PMID: 16474519     DOI: 10.1038/ncpuro0054

Source DB:  PubMed          Journal:  Nat Clin Pract Urol        ISSN: 1743-4270


  5 in total

Review 1.  Pathophysiology of overactive bladder.

Authors:  Mai A Banakhar; Tariq F Al-Shaiji; Magdy M Hassouna
Journal:  Int Urogynecol J       Date:  2012-02-07       Impact factor: 2.894

2.  Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation.

Authors:  Wenkuan Xin; Rupal P Soder; Qiuping Cheng; Eric S Rovner; Georgi V Petkov
Journal:  Am J Physiol Cell Physiol       Date:  2012-09-19       Impact factor: 4.249

3.  Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder.

Authors:  Franz Sprossmann; Patrick Pankert; Ulrike Sausbier; Angela Wirth; Xiao-Bo Zhou; Johannes Madlung; Hong Zhao; Iancu Bucurenciu; Andreas Jakob; Tobias Lamkemeyer; Winfried Neuhuber; Stefan Offermanns; Michael J Shipston; Michael Korth; Alfred Nordheim; Peter Ruth; Matthias Sausbier
Journal:  FEBS J       Date:  2008-02-12       Impact factor: 5.542

4.  Development and changes with age of detrusor overactivity in spontaneous hypertensive rats as observed by simultaneous registrations of intravesical and intraabdominal pressures.

Authors:  Long-Hu Jin; Hun-Jae Lee; Hwa-Yoan Shin; Bo-Hwa Choi; Sang-Min Yoon; Chang-Shin Park; Tack Lee
Journal:  Int Neurourol J       Date:  2011-12-31       Impact factor: 2.835

Review 5.  Overactive Bladder Symptoms Within Nervous System: A Focus on Etiology.

Authors:  Chuying Qin; Yinhuai Wang; Yunliang Gao
Journal:  Front Physiol       Date:  2021-12-10       Impact factor: 4.566

  5 in total

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