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Literature DB >> 164740

Unsuccessful trial of gene replacement in arginase deficiency.

H G Terheggen, A Lowenthal, F Lavinha, J P Colombo, S Rogers.

Abstract

The Shope virus following cutaneous inoculation produces skin papillomas in rabbits and induces a virus-coded arginase in the squameous epithelium of these papillomas. The only discernible effect of the virus inoculated intravenously in rabbits and other animals was a decrease of the serum arginine concentration. Intravenous injection in 3 hyperargininemic patients, however, did not influence the underlying metabolic disease.

Entities: Chemical Disease Species

Mesh：

Substances：
Arginine

Year: 1975 PMID： 164740 DOI： 10.1007/bf00464689

Source DB: PubMed Journal: Z Kinderheilkd ISSN： 0044-2917

9 in total

1. Induction of arginase in rabbit epithelium by the Shope rabbit papilloma virus.

Authors: S ROGERS
Journal: Nature Date: 1959-06-27 Impact factor: 49.962

2. Shope papilloma virus: a passenger in man and its significance to the potential control of the host genome.

Authors: S Rogers
Journal: Nature Date: 1966-12-10 Impact factor: 49.962

3. Gene therapy for human genetic disease?

Authors:
Journal: Science Date: 1972-11-10 Impact factor: 47.728

4. Familial hyperargininemia.

Authors: H G Terheggen; F Lavinha; J P Colombo; M Van Sande; A Lowenthal
Journal: J Genet Hum Date: 1972-03

5. [Hyperargininemia wityh arginase deficiency. A new familial metabolic disease. I. Clinical studies].

Authors: H G Terheggen; A Schwenk; A Lowenthal; M van Sande; J P Colombo
Journal: Z Kinderheilkd Date: 1970

6. [Hyperargininemia with arginase deficiency. A new familial metabolic disease. II. Biochemical studies].

Authors: H G Terheggen; A Schwenk; A Lowenthal; M van Sande; J P Colombo
Journal: Z Kinderheilkd Date: 1970

7. Change in the structure of Shope papilloma virus-induced arginase associated with mutation of the virus.

Authors: S Rogers
Journal: J Exp Med Date: 1971-12-01 Impact factor: 14.307

8. Induction of arginase activity with the Shope papilloma virus in tissue culture cells from an argininemic patient.

Authors: S Rogers; A Lowenthal; H G Terheggen; J P Columbo
Journal: J Exp Med Date: 1973-04-01 Impact factor: 14.307

9. Studies of the mechanism of action of the Shope rabbit papilloma virus. I. Concerning the nature of the induction of arginase in the infected cells.

Authors: S ROGERS; M MOORE
Journal: J Exp Med Date: 1963-03-01 Impact factor: 14.307

9 in total

20 in total

Review 1. Gene therapy: light is finally in the tunnel.

Authors: Huibi Cao; Robert S Molday; Jim Hu
Journal: Protein Cell Date: 2012-01-10 Impact factor: 14.870

2. Clinical application of somatic gene therapy in inborn errors of metabolism.

Authors: F D Ledley
Journal: J Inherit Metab Dis Date: 1990 Impact factor: 4.982

3. Human hyperargininemia: a mutation not expressed in skin fibroblasts?

Authors: A F Van Elsen; J G Leroy
Journal: Am J Hum Genet Date: 1977-07 Impact factor: 11.025

Review 4. Genetic engineering: moral aspects and control of practice.

Authors: V H Eisenberg; J G Schenker
Journal: J Assist Reprod Genet Date: 1997-07 Impact factor: 3.412

Review 5. Arginase-1 deficiency.

Authors: Yuan Yan Sin; Garrett Baron; Andreas Schulze; Colin D Funk
Journal: J Mol Med (Berl) Date: 2015-10-14 Impact factor: 4.599