Literature DB >> 16473578

Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila.

Jonathan C Kagan, Takahiro Murata, Craig R Roy.   

Abstract

Legionella pneumophila is an intracellular bacterial pathogen that utilizes a type IV secretion system to subvert the function of the Rab1 GTPase. Bacterial proteins translocated into host cells mediate the accumulation of the Rab1 protein on vacuoles containing Legionella pneumophila. Assays used to investigate recruitment of Rab1 by L. pneumophila are described. These assays can be used to determine host and bacterial factors required for L. pneumophila subversion of the host secretory pathway.

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Year:  2005        PMID： 16473578     DOI： 10.1016/S0076-6879(05)03007-7

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  7 in total

1.  Type II Secretion Is Necessary for Optimal Association of the Legionella-Containing Vacuole with Macrophage Rab1B but Enhances Intracellular Replication Mainly by Rab1B-Independent Mechanisms.

Authors:  Richard C White; Nicholas P Cianciotto
Journal:  Infect Immun       Date:  2016-11-18       Impact factor: 3.441

Review 2.  Manipulation of host membrane machinery by bacterial pathogens.

Authors:  Pascale Cossart; Craig R Roy
Journal:  Curr Opin Cell Biol       Date:  2010-06-09       Impact factor: 8.382

3.  The iron-regulated vacuolar Legionella pneumophila MavN protein is a transition-metal transporter.

Authors:  Eric T Christenson; Dervla T Isaac; Karin Yoshida; Erion Lipo; Jin-Sik Kim; Rodolfo Ghirlando; Ralph R Isberg; Anirban Banerjee
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-20       Impact factor: 11.205

4.  Structural analysis of Brucella abortus RicA substitutions that do not impair interaction with human Rab2 GTPase.

Authors:  Bernard Nkengfac; Jenny Pouyez; Emilie Bauwens; Jean Vandenhaute; Jean-Jacques Letesson; Johan Wouters; Xavier De Bolle
Journal:  BMC Biochem       Date:  2012-08-14       Impact factor: 4.059

Review 5.  Legionella pneumophila Dot/Icm translocated substrates: a sum of parts.

Authors:  Alexander W Ensminger; Ralph R Isberg
Journal:  Curr Opin Microbiol       Date:  2009-01-20       Impact factor: 7.934

6.  AMPylation is critical for Rab1 localization to vacuoles containing Legionella pneumophila.

Authors:  Camille A Hardiman; Craig R Roy
Journal:  MBio       Date:  2014-02-11       Impact factor: 7.867

7.  The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.

Authors:  Andree Hubber; Kohei Arasaki; Fubito Nakatsu; Camille Hardiman; David Lambright; Pietro De Camilli; Hiroki Nagai; Craig R Roy
Journal:  PLoS Pathog       Date:  2014-07-03       Impact factor: 6.823
  7 in total

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