Literature DB >> 16473309

HLA genes in Southern Tunisians (Ghannouch area) and their relationship with other Mediterraneans.

A Hajjej1, S Hmida, H Kaabi, A Dridi, A Jridi, A El Gaa l ed, K Boukef.   

Abstract

South Tunisian HLA gene profile has studied for the first time. HLA-A, -B, -DRB1 and -DQB1 allele frequencies of Ghannouch have been compared with those of neighboring populations, other Mediterraneans and Sub-Saharans. Their relatedness has been tested by genetic distances, Neighbor-Joining dendrograms and correspondence analyses. Our HLA data show that both southern from Ghannouch and northern Tunisians are of a Berber substratum in spite of the successive incursions (particularly, the 7th-8th century A.D. Arab invasion) occurred in Tunisia. It is also the case of other North Africans and Iberians. This present study confirms the relatedness of Greeks to Sub-Saharan populations. This suggests that there was an admixture between the Greeks and Sub-Saharans probably during Pharaonic period or after natural catastrophes (dryness) occurred in Sahara.

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Year:  2005        PMID: 16473309     DOI: 10.1016/j.ejmg.2005.01.001

Source DB:  PubMed          Journal:  Eur J Med Genet        ISSN: 1769-7212            Impact factor:   2.708


  8 in total

1.  The investigation of the origin of Southern Tunisians using HLA genes.

Authors:  Abdelhafidh Hajjej; Wassim Y Almawi; Lasmar Hattab; Amel El-Gaaied; Slama Hmida
Journal:  J Hum Genet       Date:  2016-11-24       Impact factor: 3.172

Review 2.  The human leukocyte antigen class I genes in nasopharyngeal carcinoma risk.

Authors:  Elham Hassen; Ghandri Nahla; Noureddine Bouaouina; Lotfi Chouchane
Journal:  Mol Biol Rep       Date:  2009-05-17       Impact factor: 2.316

3.  HLA-B, DR and DQ antigens polymorphism in Tunisian patients with ankylosing spondylitis (a case-control study).

Authors:  Mohamed Montacer Kchir; Wafa Hamdi; Lilia Laadhar; Samir Kochbati; Dhia Kaffel; Kaouthar Saadellaoui; Houria Lahmar; Mohamed Mehdi Ghannouchi; Dhouha Azzouz; Lilia Daoud; Abdelmajid Ben Hamida; Béchir Zouari; Mondher Zitouni; Sondes Makni
Journal:  Rheumatol Int       Date:  2009-08-05       Impact factor: 2.631

4.  Abdominal vs. overall obesity among women in a nutrition transition context: geographic and socio-economic patterns of abdominal-only obesity in Tunisia.

Authors:  Pierre Traissac; Rebecca Pradeilles; Jalila El Ati; Hajer Aounallah-Skhiri; Sabrina Eymard-Duvernay; Agnès Gartner; Chiraz Béji; Souha Bougatef; Yves Martin-Prével; Patrick Kolsteren; Francis Delpeuch; Habiba Ben Romdhane; Bernard Maire
Journal:  Popul Health Metr       Date:  2015-01-24

5.  HLA Class I and Class II Alleles and Haplotypes Confirm the Berber Origin of the Present Day Tunisian Population.

Authors:  Abdelhafidh Hajjej; Wassim Y Almawi; Lasmar Hattab; Amel El-Gaaied; Slama Hmida
Journal:  PLoS One       Date:  2015-08-28       Impact factor: 3.240

6.  The genetic heterogeneity of Arab populations as inferred from HLA genes.

Authors:  Abdelhafidh Hajjej; Wassim Y Almawi; Antonio Arnaiz-Villena; Lasmar Hattab; Slama Hmida
Journal:  PLoS One       Date:  2018-03-09       Impact factor: 3.240

7.  Genetics and genomic medicine in Tunisia.

Authors:  Houda Elloumi-Zghal; Habiba Chaabouni Bouhamed
Journal:  Mol Genet Genomic Med       Date:  2018-03       Impact factor: 2.183

8.  Evidence for association of the E23K variant of KCNJ11 gene with type 2 diabetes in Tunisian population: population-based study and meta-analysis.

Authors:  Khaled Lasram; Nizar Ben Halim; Sana Hsouna; Rym Kefi; Imen Arfa; Welid Ghazouani; Henda Jamoussi; Houda Benrahma; Najla Kharrat; Ahmed Rebai; Slim Ben Ammar; Sonia Bahri; Abdelhamid Barakat; Abdelmajid Abid; Sonia Abdelhak
Journal:  Biomed Res Int       Date:  2014-07-07       Impact factor: 3.411

  8 in total

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