Literature DB >> 16473243

Imatinib as a cause of cystoid macular edema following uneventful phacoemulsification surgery.

Imran Masood1, Anil Negi, Harminder S Dua.   

Abstract

Cystoid macular edema (CME) is an important cause of visual impairment following phacoemulsification surgery. Imatinib is a new drug that is being used as adjunctive therapy in the management of various malignancies. A reported ocular side effect of this drug is spontaneous retinal edema. We report the case of a patient on imatinib who developed significant premature CME following uneventful phacoemulsification surgery. This resolved soon after cessation of imatinib therapy, and there was an improvement in visual acuity.

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Year:  2005        PMID： 16473243     DOI： 10.1016/j.jcrs.2005.10.029

Source DB:  PubMed          Journal:  J Cataract Refract Surg        ISSN： 0886-3350            Impact factor:   3.351


  6 in total

1.  Bilateral cystoid macular edema in a patient with chronic myeloid leukaemia under treatment with imanitib mesylate: report of an unusual side effect.

Authors:  Ilias Georgalas; Carlos Pavesio; Eric Ezra
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2007-06-12       Impact factor: 3.117

2.  Periorbital edema secondary to imatinib mesylate.

Authors:  Collin M McClelland; George J Harocopos; Philip L Custer
Journal:  Clin Ophthalmol       Date:  2010-05-14

Review 3.  Drug-induced macular edema.

Authors:  Olga E Makri; Ilias Georgalas; Constantine D Georgakopoulos
Journal:  Drugs       Date:  2013-06       Impact factor: 9.546

Review 4.  Ocular Toxicity of Targeted Anticancer Agents.

Authors:  Blake H Fortes; Prashant D Tailor; Lauren A Dalvin
Journal:  Drugs       Date:  2021-03-31       Impact factor: 9.546

5.  Intravitreal bevacizumab and triamcinolone for treatment of cystoid macular oedema associated with chronic myeloid leukaemia and imatinib therapy.

Authors:  Eric K Newcott; Abdallah A Ellabban; Shokufeh Tavassoli; Ahmed Sallam
Journal:  Case Rep Ophthalmol Med       Date:  2015-02-04

6.  Imatinib induces apoptosis by inhibiting PDGF- but not insulin-induced PI 3-kinase/Akt survival signaling in RGC-5 retinal ganglion cells.

Authors:  Swarajit K Biswas; Yan Zhao; Lakshman Sandirasegarane
Journal:  Mol Vis       Date:  2009-08-15       Impact factor: 2.367
  6 in total

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