Literature DB >> 16472698

Using three-dimensional acinar structures for molecular and cell biological assays.

Bin Xiang1, Senthil K Muthuswamy.   

Abstract

Epithelial cells grown in three-dimensional matrix allows one to investigate biological processes in a setting that is closer to in vivo conditions than those obtained by growing cells on plastic culture dishes. Here we outline procedures that allow one to investigate molecular mechanisms that regulate formation and disruption of three-dimensional epithelial structures.

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Year:  2006        PMID： 16472698     DOI： 10.1016/S0076-6879(06)06054-X

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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