Literature DB >> 16472209

5-Lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents.

Josef Jampilek1, Martin Dolezal, Veronika Opletalova, Jiri Hartl.   

Abstract

Leukotrienes play an important role in the inflammatory process accompanying allergic diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are generated from arachidonic acid as a result of the 5-lipoxygenase action. This paper deals with 5-lipoxygenase action mechanism and the following biosynthesis of all leukotrienes. In this article, potential antileukotrienic agents are classified according to their mechanism of action. The original antileukotrienic compounds of the Research Institute for Pharmacy and Biochemistry in Prague (VUFB), Czech Republic are presented in a separate chapter of the paper.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16472209     DOI： 10.2174/092986706775197935

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN： 0929-8673            Impact factor:   4.530


  9 in total

1.  Kinetic and structural investigations into the allosteric and pH effect on the substrate specificity of human epithelial 15-lipoxygenase-2.

Authors:  Netra Joshi; Eric K Hoobler; Steven Perry; Giovanni Diaz; Brian Fox; Theodore R Holman
Journal:  Biochemistry       Date:  2013-10-30       Impact factor: 3.162

Review 2.  Chronic Inflammatory Diseases, Anti-Inflammatory Agents and Their Delivery Nanosystems.

Authors:  Daniela Placha; Josef Jampilek
Journal:  Pharmaceutics       Date:  2021-01-06       Impact factor: 6.321

Review 3.  Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red".

Authors:  James J Lee; Elizabeth A Jacobsen; Sergei I Ochkur; Michael P McGarry; Rachel M Condjella; Alfred D Doyle; Huijun Luo; Katie R Zellner; Cheryl A Protheroe; Lian Willetts; William E Lesuer; Dana C Colbert; Richard A Helmers; Paige Lacy; Redwan Moqbel; Nancy A Lee
Journal:  J Allergy Clin Immunol       Date:  2012-09       Impact factor: 10.793

Review 4.  Recent development of lipoxygenase inhibitors as anti-inflammatory agents.

Authors:  Chaoyu Hu; Shutao Ma
Journal:  Medchemcomm       Date:  2017-11-29       Impact factor: 3.597

Review 5.  Asthma genetics and personalised medicine.

Authors:  Deborah A Meyers; Eugene R Bleecker; John W Holloway; Stephen T Holgate
Journal:  Lancet Respir Med       Date:  2014-05-02       Impact factor: 30.700

6.  Bioassay-guided isolation, identification and molecular ligand-target insight of lipoxygenase inhibitors from leaves of Anisomeles malabarica R.Br.

Authors:  A Sudha; P Srinivasan
Journal:  Pharmacogn Mag       Date:  2014-08       Impact factor: 1.085

7.  Investigating the activity spectrum for ring-substituted 8-hydroxyquinolines.

Authors:  Robert Musiol; Josef Jampilek; Jacek E Nycz; Matus Pesko; James Carroll; Katarina Kralova; Marcela Vejsova; Jim O'Mahony; Aidan Coffey; Anna Mrozek; Jaroslaw Polanski
Journal:  Molecules       Date:  2010-01-12       Impact factor: 4.411

8.  Investigating biological activity spectrum for novel styrylquinazoline analogues.

Authors:  Josef Jampilek; Robert Musiol; Jacek Finster; Matus Pesko; James Carroll; Katarina Kralova; Marcela Vejsova; Jim O'Mahony; Aidan Coffey; Jiri Dohnal; Jaroslaw Polanski
Journal:  Molecules       Date:  2009-10-23       Impact factor: 4.411

9.  Investigation of Anti-Inflammatory Potential of N-Arylcinnamamide Derivatives.

Authors:  Jan Hošek; Jiří Kos; Tomáš Strhársky; Lucie Černá; Pavel Štarha; Ján Vančo; Zdeněk Trávníček; Ferdinand Devínsky; Josef Jampílek
Journal:  Molecules       Date:  2019-12-11       Impact factor: 4.411
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.