Literature DB >> 1647215

Protein phosphatase 2Bw and protein phosphatase Z are Saccharomyces cerevisiae enzymes.

E F Da Cruz e Silva1, V Hughes, P McDonald, M J Stark, P T Cohen.   

Abstract

cDNAs encoding three protein phosphatases, termed PP2Bw (Da Cruz e Silva, E.F. and Cohen, P.T.W. (1989) Biochim. Biophys. Acta 1009, 293-296), PPZ1 and PPZ2 that have been isolated from a Clontech 'rabbit brain' library are shown to be Saccharomyces cerevisiae clones. PPZ1 and PPZ2 are two novel yeast phosphatases showing 93% amino acid sequence identity to one another. PPZ1 shows approx. 60% sequence identity to S. cerevisiae or mammalian PP1 and approx. 40% identity to S. cerevisiae or mammalian PP2A. These and other observations suggest that the two isoforms of PPZ have functions distinct from those of PP1.

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Year:  1991        PMID: 1647215     DOI: 10.1016/0167-4781(91)90023-f

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  14 in total

1.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1992-05-11       Impact factor: 16.971

Review 2.  The regulation and function of protein phosphatases in the brain.

Authors:  A T Sim
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

3.  Molecular cloning of a calmodulin-dependent phosphatase from murine testis: identification of a developmentally expressed nonneural isoenzyme.

Authors:  T Muramatsu; P R Giri; S Higuchi; R L Kincaid
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-15       Impact factor: 11.205

4.  Functional analysis of the yeast Glc7-binding protein Reg1 identifies a protein phosphatase type 1-binding motif as essential for repression of ADH2 expression.

Authors:  K M Dombek; V Voronkova; A Raney; E T Young
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272

Review 5.  Serine/threonine protein phosphatases.

Authors:  S Wera; B A Hemmings
Journal:  Biochem J       Date:  1995-10-01       Impact factor: 3.857

6.  Genetic interactions between GLC7, PPZ1 and PPZ2 in saccharomyces cerevisiae.

Authors:  G M Venturi; A Bloecher; T Williams-Hart; K Tatchell
Journal:  Genetics       Date:  2000-05       Impact factor: 4.562

7.  Immunological approach to identify calmodulin-stimulated phosphatase isozymes from bovine brain.

Authors:  N Yokoyama; T Kuno; S Furuyama; J H Wang
Journal:  Mol Cell Biochem       Date:  1994-03-30       Impact factor: 3.396

8.  Calcineurin involvement in the regulation of high-threshold Ca2+ channels in NG108-15 (rodent neuroblastoma x glioma hybrid) cells.

Authors:  E A Lukyanetz; T P Piper; T S Sihra
Journal:  J Physiol       Date:  1998-07-15       Impact factor: 5.182

9.  Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis.

Authors:  M Shimanuki; N Kinoshita; H Ohkura; T Yoshida; T Toda; M Yanagida
Journal:  Mol Biol Cell       Date:  1993-03       Impact factor: 4.138

Review 10.  Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae.

Authors:  V J Cid; A Durán; F del Rey; M P Snyder; C Nombela; M Sánchez
Journal:  Microbiol Rev       Date:  1995-09
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