| Literature DB >> 16469692 |
Abstract
Understanding the molecular mechanisms that control the architecture of organelles is an area of intense study. In this issue of Cell, Voeltz et al. (2006) report that two membrane proteins, Rtn4a/NogoA and DP1/Yop1p, are responsible for the generation of tubular morphology in the endoplasmic reticulum (ER). The unusual membrane topology of these proteins may directly contribute to ER curvature.Entities:
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Year: 2006 PMID： 16469692 DOI： 10.1016/j.cell.2006.01.017
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582